3-Hydroxy,3-Methylglutarate

3-hydroxy,3-methylglutarate (HMG) is an organic acid produced during the breakdown of certain amino acids and fats. This urine test detects abnormal levels of HMG, which may indicate a rare metabolic disorder called HMG-CoA lyase deficiency. In this condition, the body cannot properly break down certain nutrients, leading to a dangerous buildup of acids in the blood. Early detection through urine screening is important for managing this inherited metabolic condition and preventing serious complications.