3-Hydroxyadipate

3-hydroxyadipate is an organic acid produced during the breakdown of certain amino acids, particularly lysine and tryptophan. This urine test detects abnormal levels that may indicate a rare metabolic disorder affecting amino acid metabolism. Elevated 3-hydroxyadipate can be associated with conditions like 3-hydroxyacyl-CoA dehydrogenase deficiency or other metabolic disturbances. This test is typically ordered when patients have unexplained symptoms, developmental concerns, or abnormal newborn screening results, allowing early diagnosis and intervention to manage the metabolic condition effectively.