3-Hydroxyglutarate

ChemistryAlso known as: 3oh-glutaric acidAlso known as: 3-Hydroxyglutaric acidumol/L

Measures 3-hydroxyglutarate, an organic acid in blood.

Normal Range

0 – 5 umol/L

umol/L

Abnormal Levels

Consult your provider

Specimen Type

Blood

Why This Biomarker Matters

Elevated 3-HG may indicate rare metabolic disorders affecting amino acid metabolism. This helps diagnose genetic conditions causing neurological or developmental problems.

Understanding Your Results

Normal Range

0 – 5 umol/L

Overview

3-hydroxyglutarate (3-HG) is an organic acid produced during normal amino acid metabolism. Elevated blood levels may indicate rare metabolic disorders affecting glutamic acid metabolism or certain genetic conditions. This test helps identify inborn errors of metabolism that could cause neurological symptoms, developmental delays, or organ dysfunction. Abnormal accumulation of this compound interferes with normal cellular energy production and protein synthesis.

Technical Information (LOINC Codes)

Standardized laboratory codes for this biomarker

69851-4Primary

3-Hydroxyglutarate [Moles/volume] in Serum or Plasma

umol/L

29624-4

3-Hydroxyglutarate [Presence] in Urine

69837-3

3-Hydroxyglutarate [Moles/volume] in Cerebral spinal fluid

umol/L

69850-6

3-Hydroxyglutarate [Moles/volume] in Amniotic fluid

umol/L

82505-9

3-Hydroxyglutarate [Moles/volume] in DBS

nmol/mL

Available Lab Tests

Order tests that measure this biomarker

Urinary Organic Acids

$586.08

Results in 7-14 business days