Actin.smooth muscle Ab.IgG

This test detects IgG antibodies against smooth muscle actin, a protein found in smooth muscle tissue. Positive results suggest autoimmune liver disease, particularly autoimmune hepatitis. In this condition, the immune system mistakenly attacks the liver, causing inflammation and potential cirrhosis if untreated. This antibody is relatively specific for autoimmune hepatitis and helps distinguish it from other liver diseases. Early diagnosis is crucial because immunosuppressive therapy can effectively manage the condition and prevent liver damage.