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Beta-2-Microglobulin
Detects beta-2-microglobulin protein in serum or plasma.
Why This Biomarker Matters
Elevated CSF beta-2-microglobulin suggests central nervous system infection, inflammation, or malignancy requiring urgent diagnosis and treatment.
Overview
Beta-2-microglobulin (B2M) is a small protein found on the surface of most nucleated cells and is a component of the MHC class I complex. This test measures B2M concentration in serum or plasma. Elevated serum levels are an important prognostic marker in multiple myeloma and other lymphoproliferative disorders. B2M also rises with renal impairment (since it is filtered by the kidneys), chronic inflammatory conditions, and certain viral infections including HIV. Serial measurements are used to monitor treatment response in hematologic malignancies.
Technical Information (LOINC Codes)
Standardized laboratory codes for this biomarker
1952-1Primary43919-010873-814626-61951-343818-41953-950824-254356-156662-059217-059218-876484-583076-083077-883078-683079-488711-732301-432302-239458-543819-248166-349081-3Available Lab Tests
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