Calcium oxalate crystals

ChemistryAlso known as: CaOx Cry # Ur Comp AssistAlso known as: CaOx Cry #/area UrAlso known as: CaOx Cry #/area Ur Comp Assist/uL

Counts calcium oxalate crystals present in urine.

Normal Range
Consult your provider
/uL
Abnormal Levels
Consult your provider
Specimen Type
Blood

Why This Biomarker Matters

Elevated crystals indicate higher kidney stone risk. This prompts dietary changes to reduce oxalate intake, increase hydration, and investigation of underlying metabolic abnormalities.

Overview

This test quantifies calcium oxalate crystals in urine, which form when calcium and oxalate concentrations are high. Elevated levels increase kidney stone risk, particularly in people with genetic predisposition, high dietary oxalate, dehydration, or certain metabolic disorders. A positive result warrants dietary modifications (reducing oxalate, increasing hydration) and further evaluation for underlying causes like hyperoxaluria or hypercalcemia.

Research & Evidence

99 publications

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Circular cell clusters and calcium oxalate crystals: critical players in Solanaceae anther dehiscence.
Planta · 2025
PMID: 40299132Review
Tamm-Horsfall protein biosensors for management of nephrolithiasis.
Clin Chim Acta · 2025
PMID: 41456739Review
The Distinction of Chemical Profiles of Mountainous Forest Cultivated Ginseng and Garden Ginseng Based on Calcium Oxalate Crystals, Organic Acids, and Ginsenosides.
Foods · 2025
PMID: 40941189Other
Effects of calcium oxalate crystals on neutrophil cellular proteome and functions: implications for nephrolithiasis.
Cell Commun Signal · 2025
PMID: 40646566Other
Correlative microscopy for in-depth analysis of calcium oxalate crystals in plant tissues.
Plant Methods · 2025
PMID: 41139788Other
Calcium Oxalate Crystals with a Bipyramidal Morphology and a High Tendency to Aggregate Attach Directly to Breast Cancer Cells and Affect Their Phenotype.
ACS Appl Mater Interfaces · 2025
PMID: 41036783Other
Antiurolithiatic Potential of a Series of Phthalimide Derivatives on Calcium Oxalate Crystals.
Chem Biodivers · 2026
PMID: 41503920Preclinical
Clinical Approaches and Emerging Therapeutic Horizons in Primary Hyperoxaluria.
J Clin Med · 2026
PMID: 41682620
Mechanistic Insights into Calcium Oxalate Crystals in Aspergillosis of the Maxillary Sinus.
Head Neck Pathol · 2026
PMID: 41627592
ER stress induced extracellular vesicles secretion from macrophages promotes calcium oxalate crystals formation in kidney.
Mol Biomed · 2025
PMID: 41247622Preclinical

Research data from MEDLINE/PubMed · 99 articles

Technical Information (LOINC Codes)

Standardized laboratory codes for this biomarker

53296-0Primary
Calcium oxalate crystals [#/volume] in Urine by Computer assisted method
/uL
53131-9
Calcium oxalate crystals [#/area] in Urine sediment by Microscopy low power field
/[LPF]
33234-6
Calcium oxalate crystals [Presence] in Urine by Computer assisted method
25148-8
Calcium oxalate crystals [#/area] in Urine sediment by Microscopy high power field
/[HPF]
53306-7
Calcium oxalate crystals [#/area] in Urine by Computer assisted method
/[HPF]
5774-5
Calcium oxalate crystals [Presence] in Urine sediment by Light microscopy
105897-3
Calcium oxalate crystals [#/area] in Urine
/[LPF]
105896-5
Calcium oxalate crystals [#/area] in Urine sediment
/[LPF]
105053-3
Calcium oxalate crystals [Presence] in Urine sediment by Microscopy
101931-4
Calcium oxalate crystals [Energy Difference] in Urine
kJ/mol

Available Lab Tests

Order tests that measure this biomarker

Urinalysis Complete

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Urinalysis Complete Test with Reflex to Culture

$24.64