Ceruloplasmin

Ceruloplasmin is a protein produced by the liver that binds and transports copper in the bloodstream. Low ceruloplasmin levels are a hallmark sign of Wilson's disease, a rare genetic disorder where copper accumulates to toxic levels in organs like the brain, liver, and eyes. Symptoms include liver disease, tremors, behavioral changes, and a characteristic golden-brown ring in the eye (Kayser-Fleischer ring). Early detection through ceruloplasmin testing is crucial because Wilson's disease is treatable with copper-reducing medications.