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Gliadin peptide+Tissue transglutaminase Ab.IgA+IgG
Detects antibodies against gluten-related proteins and an intestinal enzyme, indicating celiac disease.
Why This Biomarker Matters
Positive results suggest celiac disease, requiring dietary gluten elimination and further testing. Early diagnosis prevents intestinal damage and nutrient deficiencies.
Overview
This test detects antibodies (IgA and IgG) against gliadin and tissue transglutaminase, key markers for celiac disease screening. When people with celiac disease consume gluten, their immune system attacks intestinal tissue and produces these antibodies. A positive result strongly suggests celiac disease and warrants further testing with small intestinal biopsy for confirmation. Early detection is important because untreated celiac disease can cause intestinal damage, nutrient malabsorption, and long-term complications including osteoporosis and increased infection risk.
Technical Information (LOINC Codes)
Standardized laboratory codes for this biomarker
63420-4PrimaryAvailable Lab Tests
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