Hydroxyproline

ChemistryAlso known as: L-HydroxyprolineAlso known as: 4-hydroxyprolineN/A

Screens for abnormal hydroxyproline levels in blood.

Normal Range

Consult your provider

N/A

Abnormal Levels

Consult your provider

Specimen Type

Blood

Why This Biomarker Matters

Abnormal hydroxyproline levels may indicate collagen disorders, bone disease, arthritis, or liver dysfunction. Testing helps assess connective tissue and bone health.

Overview

Hydroxyproline is an amino acid found almost exclusively in collagen, the structural protein in skin, bones, joints, and connective tissue. This qualitative test screens for abnormal hydroxyproline levels, which may indicate collagen metabolism disorders, bone disease, liver disease, or connective tissue problems. Elevated levels can reflect increased collagen breakdown (from arthritis or injury) or impaired collagen synthesis. This test helps assess bone and connective tissue health.

Technical Information (LOINC Codes)

Standardized laboratory codes for this biomarker

2445-5Primary

Hydroxyproline [Presence] in Serum or Plasma

2451-3

Hydroxyproline [Mass/volume] in Urine

mg/dL

2446-3

Hydroxyproline [Mass/volume] in Serum or Plasma

mg/dL

2447-1

Hydroxyproline [Mass/time] in 24 hour Urine

mg/(24.h)

14785-0

Hydroxyproline [Moles/time] in 24 hour Urine

umol/(24.h)

26596-7

Hydroxyproline [Moles/volume] in Cerebral spinal fluid

umol/L

20647-4

Hydroxyproline [Moles/volume] in Serum or Plasma

umol/L

27181-7

Hydroxyproline [Moles/volume] in Amniotic fluid

umol/dL

32249-5

Hydroxyproline [Moles/volume] in Body fluid

umol/L

32250-3

Hydroxyproline [Moles/volume] in Vitreous fluid

umol/L

47651-5

Hydroxyproline [Moles/volume] in DBS

umol/L

12720-9

Hydroxyproline [Mass/volume] in 2 hour Urine

mg/dL

59392-1

Hydroxyproline [Mass/volume] in 24 hour Urine

mg/L

13374-4

Hydroxyproline [Mass/volume] in Cerebral spinal fluid

mg/dL

13401-5

Hydroxyproline [Mass/volume] in Amniotic fluid

mg/dL

17001-9

Hydroxyproline [Presence] in Urine

25934-1

Hydroxyproline [Moles/volume] in 24 hour Urine

umol/L

26740-1

Hydroxyproline [Moles/volume] in Urine

umol/L

26810-2

Hydroxyproline [Presence] in 24 hour Urine

Available Lab Tests

Order tests that measure this biomarker

Amino Acids (Plasma)

$193.00

Results in 3-7 business days