PHENobarbital

ToxicologyAlso known as: 5-Ethyl-5-phenylbarbituric acidAlso known as: Phenobarbitoneug/mL

Measures phenobarbital concentration in the blood.

Normal Range
Consult your provider
ug/mL
Abnormal Levels
Consult your provider
Specimen Type
Blood

Why This Biomarker Matters

Essential for ensuring safe and effective seizure control. Monitoring prevents both therapeutic failure (too low) and toxicity (too high) from this long-acting barbiturate.

Overview

This test measures phenobarbital, a long-acting barbiturate medication used to treat seizures and manage certain neurological conditions. Testing is essential for therapeutic drug monitoring—ensuring levels stay within the effective range without causing toxicity. Phenobarbital accumulates in the body over time, requiring careful monitoring. Levels may be checked when starting therapy, adjusting doses, or investigating symptoms like excessive sedation. The medication is metabolized slowly, so testing helps prevent overdose and maintain seizure control.

Research & Evidence

22 publications

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Research data from MEDLINE/PubMed · 22 articles

Technical Information (LOINC Codes)

Standardized laboratory codes for this biomarker

3948-7Primary
PHENobarbital [Mass/volume] in Serum or Plasma
ug/mL
27051-2
PHENobarbital [Mass/volume] in Milk
ug/mL
72396-5
PHENobarbital [Mass/volume] in Blood by Confirmatory method
ng/mL
14874-2
PHENobarbital [Moles/volume] in Serum or Plasma
umol/L
19666-7
PHENobarbital [Presence] in Urine by Screen method
72628-1
PHENobarbital [Presence] in Saliva (oral fluid) by Confirmatory method
72453-4
PHENobarbital [Mass/volume] in Saliva (oral fluid) by Confirmatory method
ng/mL
4393-5
PHENobarbital [Mass] of Dose
mg
82970-5
PHENobarbital [Mass/volume] in Serum, Plasma or Blood by Confirmatory method
ug/mL
60468-6
PHENobarbital [Mass/volume] in Serum or Plasma by Confirmatory method
ug/mL
3947-9
PHENobarbital [Presence] in Serum or Plasma
32108-3
PHENobarbital [Presence] in Specimen
3950-3
PHENobarbital [Mass/volume] in Urine
ug/mL
3949-5
PHENobarbital [Presence] in Urine
16192-7
PHENobarbital [Presence] in Urine by Confirmatory method
16241-2
PHENobarbital [Mass/volume] in Urine by Confirmatory method
ng/mL
27235-1
PHENobarbital [Mass/mass] in Meconium
ug/g
39487-4
PHENobarbital [Moles/volume] in Urine
umol/L
27191-6
PHENobarbital [Mass/volume] in Vitreous fluid
ug/mL
47124-3
PHENobarbital [Moles/volume] in Gastric fluid
umol/L
26905-0
PHENobarbital [Mass/mass] in Hair
ng/g
17436-7
PHENobarbital [Mass/volume] in Gastric fluid
ug/mL
29223-5
PHENobarbital [Mass/volume] in Body fluid
mg/L
12501-3
PHENobarbital [Presence] in Stool
12484-2
PHENobarbital [Presence] in Gastric fluid
35631-1
PHENobarbital [Mass/volume] in Serum or Plasma by Screen method
ug/mL
27240-1
PHENobarbital [Mass/mass] in Stool
ug/g

Available Lab Tests

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