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PHENobarbital
Measures phenobarbital concentration in the blood.
Why This Biomarker Matters
Essential for ensuring safe and effective seizure control. Monitoring prevents both therapeutic failure (too low) and toxicity (too high) from this long-acting barbiturate.
Overview
This test measures phenobarbital, a long-acting barbiturate medication used to treat seizures and manage certain neurological conditions. Testing is essential for therapeutic drug monitoring—ensuring levels stay within the effective range without causing toxicity. Phenobarbital accumulates in the body over time, requiring careful monitoring. Levels may be checked when starting therapy, adjusting doses, or investigating symptoms like excessive sedation. The medication is metabolized slowly, so testing helps prevent overdose and maintain seizure control.
Research & Evidence
22 publications
Research data from MEDLINE/PubMed · 22 articles
Technical Information (LOINC Codes)
Standardized laboratory codes for this biomarker
3948-7Primary27051-272396-514874-219666-772628-172453-44393-582970-560468-63947-932108-33950-33949-516192-716241-227235-139487-427191-647124-326905-017436-729223-512501-312484-235631-127240-1Available Lab Tests
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