Protoporphyrin.zinc

ChemistryAlso known as: ZPP Bld QlAlso known as: ZPP Bld-mCncAlso known as: ZPP Msmt RBCN/A

Detects zinc protoporphyrin in red blood cells to identify iron deficiency or lead exposure.

Normal Range
Consult your provider
N/A
Abnormal Levels
Consult your provider
Specimen Type
Blood

Why This Biomarker Matters

Elevated ZPP indicates iron deficiency or lead poisoning before other symptoms appear. Early detection prevents anemia complications and protects against lead's effects on development and cognition.

Overview

Zinc protoporphyrin (ZPP) is formed when zinc substitutes for iron in the hemoglobin production pathway. Elevated blood ZPP levels indicate iron deficiency or lead poisoning, as both interfere with normal hemoglobin synthesis. This test is particularly useful in occupational health screening and detecting iron deficiency anemia. ZPP rises before hemoglobin drops significantly, making it a sensitive early indicator of iron problems. The test is quick, non-invasive, and widely used in pediatric lead screening programs.

Technical Information (LOINC Codes)

Standardized laboratory codes for this biomarker

33007-6Primary
Protoporphyrin.zinc [Mass/volume] in Blood
ug/dL
2895-1
Protoporphyrin.zinc [Mass/volume] in Red Blood Cells
ug/dL
29763-0
Protoporphyrin.zinc [Molar ratio] in Red Blood Cells
umol/mol{Hb}
2893-6
Protoporphyrin.zinc [Presence] in Blood
2894-4
Protoporphyrin.zinc [Presence] in Red Blood Cells
34417-6
Protoporphyrin.zinc [Mass/mass] in Red Blood Cells
ug/g{Hb}
71797-5
Protoporphyrin.zinc [Moles/volume] in Red Blood Cells
umol/dL

Available Lab Tests

Order tests that measure this biomarker

Advanced Liver Health Basic

$293.92

Advanced Liver Health Comprehensive

$1044.34