Urate crystals

ChemistryAlso known as: Uric acid crystals (only reported if detected)Also known as: Monosodium urate crystalsN/A

Identifies urate crystals in stones or joint fluid using specialized analysis.

Normal Range
Consult your provider
N/A
Abnormal Levels
Consult your provider
Specimen Type
Blood

Why This Biomarker Matters

Urate crystals confirm gout or uric acid kidney stones. Identifying them guides treatment and helps prevent future attacks and kidney complications.

Overview

Urate crystals are deposits of uric acid that form in joints and tissues, causing gout—a painful inflammatory condition. This test analyzes kidney stones or joint fluid to identify whether urate crystals are present using infrared spectroscopy. Finding urate crystals confirms gout or kidney stone composition and helps guide treatment. Urate crystal formation occurs when uric acid levels become elevated, often due to diet, genetics, or certain medications.

Research & Evidence

105 publications

Sort:
Phytochemical compounds for treating hyperuricemia associated with gout: a systematic review.
Naunyn Schmiedebergs Arch Pharmacol · 2025
PMID: 39636406Meta-Analysis
Effects of bariatric surgery on hyperuricemia and gout: a systematic review of the literature.
Updates Surg · 2025
PMID: 39520613Meta-Analysis
Systematic review of the subcutaneous air pouch model using monosodium urate and calcium pyrophosphate and recommendations for studying crystal-related arthropathies.
Animal Model Exp Med · 2025
PMID: 40641359Meta-Analysis
Exploring causal pathways between hypertension, lipid levels, and gout: Insights from Mendelian randomization and NHANES observations.
Medicine (Baltimore) · 2025
PMID: 40760618Observational
Crystallization and inhibition of monosodium urate monohydrate: advances in mechanistic understanding and perspectives for gout management.
J Mater Chem B · 2026
PMID: 41397386Review
Ferroptosis in gouty arthritis: a potential therapeutic strategy.
Front Immunol · 2026
PMID: 41727428
Airborne particulate matter enhances with monosodium urate crystals the secretion of IL-1β by human immune cells.
medRxiv · 2026
PMID: 41822691
Natural products (NPs) for gout treatment in multiple targets and pathways.
Br J Pharmacol · 2026
PMID: 41787961
Plain language summary: gout remission with pegloticase.
Ther Adv Musculoskelet Dis · 2026
PMID: 41768521
IL-38 reprograms macrophage metabolism to restrain NLRP3 inflammasome assembly and attenuate monosodium urate crystals induced inflammation.
Cytokine · 2026
PMID: 41931855

Research data from MEDLINE/PubMed · 105 articles

Technical Information (LOINC Codes)

Standardized laboratory codes for this biomarker

16269-3Primary
Urate crystals [Presence] in Stone by Infrared spectroscopy
40485-5
Urate crystals [#/area] in Urine sediment by Microscopy low power field
/[LPF]
59839-1
Urate crystals [Presence] in Tissue by Light microscopy
33233-8
Urate crystals [Presence] in Urine by Computer assisted method
40682-7
Urate crystals [Presence] in Body fluid by Light microscopy
5816-4
Urate crystals [Presence] in Synovial fluid by Light microscopy
53301-8
Urate crystals [#/volume] in Urine by Computer assisted method
/uL
53311-7
Urate crystals [#/area] in Urine by Computer assisted method
/[HPF];/[LPF]
46138-4
Urate crystals [#/area] in Urine sediment by Microscopy high power field
/[HPF]
5817-2
Urate crystals [Presence] in Urine sediment by Light microscopy
99905-2
Urate crystals [#/volume] in Urine sediment by Computer assisted method
/uL
101827-4
Urate crystals [Saturation Fraction] in 24 hour Urine
kJ/mol
59279-0
Urate crystals [Presence] in Stone by X-ray diffraction
99903-7
Urate crystals [Presence] in Urine sediment by Computer assisted method
99904-5
Urate crystals [#/area] in Urine sediment by Computer assisted method
/[HPF]
101735-9
Urate crystals [Energy Difference] in 24 hour Urine
kJ/mol

Available Lab Tests

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Urinalysis Complete

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Urinalysis Complete Test with Reflex to Culture

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