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Valine
Measures the level of valine, an essential amino acid, in serum or plasma.
Why This Biomarker Matters
Abnormal valine levels can signal inherited metabolic disorders that, if caught early, can be managed to prevent serious neurological damage.
Overview
Valine is an essential amino acid your body cannot produce and must obtain from foods like meat, dairy, nuts, and legumes. This urine test measures valine levels and is typically used in genetic metabolic screening, particularly for amino acid metabolism disorders. Abnormal urine valine levels can indicate conditions like maple syrup urine disease (MSUD) or other inherited metabolic disorders affecting amino acid processing. Early detection through newborn screening or in symptomatic individuals is critical, as these conditions can cause serious neurological problems if untreated.
Research & Evidence
82 publications
Research data from MEDLINE/PubMed · 82 articles
Technical Information (LOINC Codes)
Standardized laboratory codes for this biomarker
20661-5Primary3119-526961-347799-29623-03118-73120-325553-922649-83117-913419-73116-126873-032278-432279-241169-426001-822729-8Available Lab Tests
Order tests that measure this biomarker