Overview
Acanthamoeba keratitis is a disorder.
Auto-generated from clinical reference data. Not a substitute for medical advice.
Treatments & Interventions
Research Evidence
Peer-reviewed studies linked via MeSH term "Acanthamoeba Keratitis" from the MEDLINE/PubMed database.
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Perspectives on the Incidence of Acanthamoeba Keratitis: A Systematic Review and Meta-Analysis.
[object Object], [object Object], [object Object] et al. · Ophthalmology · 2025
PMID: 39127408Meta-Analysis
Diagnostic accuracy of confocal scan in detecting acanthamoeba keratitis and fungal keratitis: a systematic review and meta-analysis.
[object Object], [object Object], [object Object] et al. · Int Ophthalmol · 2023
PMID: 36977847Meta-Analysis
Genotype distribution of Acanthamoeba in keratitis: a systematic review.
[object Object], [object Object], [object Object] · Parasitol Res · 2021
Keratitis: an update on amebicidal and cysticidal drug screening methodologies and potential treatment with azole drugs.
[object Object], [object Object], [object Object] et al. · Expert Rev Anti Infect Ther · 2021
Medical interventions for acanthamoeba keratitis.
[object Object], [object Object], [object Object] et al. · Cochrane Database Syst Rev · 2015
New approach to diagnosis and treatment of Acanthamoeba keratitis--systematic review of literature.
[object Object], [object Object], [object Object] et al. · Klin Oczna · 2012
PMID: 23461162Meta-Analysis
Microbial keratitis in overnight orthokeratology: review of the first 50 cases.
[object Object], [object Object] · Eye Contact Lens · 2005
PMID: 16163011Meta-Analysis
Rose Bengal Electromagnetic Activation with Green Light for Infection Reduction Study: A Randomized Controlled Trial.
[object Object], [object Object], [object Object] et al. · Ophthalmology · 2026
PMID: 40907580RCT
Safety and tolerability of topical polyhexamethylene biguanide: a randomised clinical trial in healthy adult volunteers.
[object Object], [object Object], [object Object] et al. · Br J Ophthalmol · 2022
PMID: 33239413RCT
A randomized masked pilot clinical trial to compare the efficacy of topical 1% voriconazole ophthalmic solution as monotherapy with combination therapy of topical 0.02% polyhexamethylene biguanide and 0.02% chlorhexidine in the treatment of Acanthamoeba keratitis.
[object Object], [object Object], [object Object] et al. · Eye (Lond) · 2021
Search all PubMed articles for Acanthamoeba keratitis
Research data from MEDLINE/PubMed
Signs & Symptoms
Based on Human Phenotype Ontology (HPO) disease-phenotype annotations.
Abnormal corneal epithelium morphology
Very frequent (80-99%)HP:0011495
Abnormality of the cornea
Very frequent (80-99%)HP:0000481
Eye pain
Very frequent (80-99%)HP:0200026
Photophobia
Very frequent (80-99%)HP:0000613
Punctate opacification of the cornea
Very frequent (80-99%)HP:0007856
Abnormality of the posterior segment of the eyeball
Frequent (30-79%)HP:0004329
Anterior uveitis
Frequent (30-79%)HP:0012122
Cataract
Frequent (30-79%)HP:0000518
Corneal hypesthesia
Frequent (30-79%)HP:0012155
Iridocele
Frequent (30-79%)HP:0100583
Iris atrophy
Frequent (30-79%)HP:0001089
Scleritis
Frequent (30-79%)HP:0100532
Anterior chamber anomalies
Occasional (5-29%)HP:0000593
Corneal stromal edema
Occasional (5-29%)HP:0012040
Corneal ulcerations
Occasional (5-29%)HP:0012804
Quick Facts
- SNOMED CT
- 231896005
- UMLS CUI
- C0000880
- Fully Specified Name
- Acanthamoeba keratitis (disorder)
- Specialists
- 0
- Diagnostic Biomarkers
- 0
- HPO Phenotypes
- 15
- Known Treatments
- 1
Medical Disclaimer
This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.
Clinical content is derived from the SNOMED CT clinical ontology and curated medical knowledge graphs.