Acquired thrombotic thrombocytopenic purpura

disorder

SNOMED 439007008CUI C2584778

Overview

Source: MedlinePlus.gov, National Library of Medicine. Not a substitute for medical advice.

Treatments & Interventions

Caplacizumab

substance

Signs & Symptoms

Based on Human Phenotype Ontology (HPO) disease-phenotype annotations.

Anti-ADAMTS13 antibody positivity

Very frequent (80-99%)HP:6000462

Low platelet count

Very frequent (80-99%)HP:0001873

Microangiopathic hemolytic anemia

Very frequent (80-99%)HP:0001937

Red or purple spots on the skin

Very frequent (80-99%)HP:0000979

Arthralgias

Frequent (30-79%)HP:0002829

Cerebral vascular events

Frequent (30-79%)HP:0001297

Confusion

Frequent (30-79%)HP:0001289

Diarrhea

Frequent (30-79%)HP:0002014

Epilepsy

Frequent (30-79%)HP:0001250

Gastro pain

Frequent (30-79%)HP:0002027

Headache

Frequent (30-79%)HP:0002315

High blood bilirubin levels

Frequent (30-79%)HP:0002904

High urine occult blood

Frequent (30-79%)HP:0000790

Increased circulating troponin I concentration

Frequent (30-79%)HP:0410173

Increased lactate dehydrogenase level

Frequent (30-79%)HP:0025435

Intestinal ischemia

Frequent (30-79%)HP:0033404

Low back pain

Frequent (30-79%)HP:0003419

Muscle pain

Frequent (30-79%)HP:0003326

Muscle weakness

Frequent (30-79%)HP:0001324

Nausea

Frequent (30-79%)HP:0002018

Panting

Frequent (30-79%)HP:0002094

Proteinuria

Frequent (30-79%)HP:0000093

Pyrexia

Frequent (30-79%)HP:0001945

Reduced haptoglobin level

Frequent (30-79%)HP:0020181

Reticulocytosis

Frequent (30-79%)HP:0001923

Schistocytes

Frequent (30-79%)HP:0001981

Stupor

Frequent (30-79%)HP:0001259

Tiredness

Frequent (30-79%)HP:0012378

Unconjugated hyperbilirubinemia

Frequent (30-79%)HP:0008282

Acute kidney injury

Occasional (5-29%)HP:0001919

Related Conditions

Drug induced thrombotic thrombocytopenic purpura(child)

Autoimmune thrombotic thrombocytopenic purpura(child)

Thrombotic thrombocytopenic purpura(parent)

Acquired platelet disorder(parent)

Acquired hemolytic anemia(parent)

Quick Facts

SNOMED CT: 439007008
UMLS CUI: C2584778
Fully Specified Name: Acquired thrombotic thrombocytopenic purpura (disorder)
Specialists: 0
Diagnostic Biomarkers: 0
HPO Phenotypes: 30
Known Treatments: 1

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Clinical content is derived from the SNOMED CT clinical ontology and curated medical knowledge graphs.