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Acrocephalosyndactyly (Apert)

disorder
SNOMED 205258009CUI C0001193

Overview

Source: MedlinePlus.gov, National Library of Medicine. Not a substitute for medical advice.

Signs & Symptoms

Based on Human Phenotype Ontology (HPO) disease-phenotype annotations.

Broad big toe
Always present (100%)HP:0010055
Bulging forehead
Always present (100%)HP:0011220
High arched palate
Always present (100%)HP:0000218
Webbed fingers
Always present (100%)HP:0010554
Webbed skin of toes
Always present (100%)HP:0010621
Acrobrachycephaly
Very frequent (80-99%)HP:0004487
Anterior bulging of the globe of eye
Very frequent (80-99%)HP:0000520
Brachyturricephaly
Very frequent (80-99%)HP:0000244
Craniosynostosis of coronal suture
Very frequent (80-99%)HP:0004440
Deformity of the skull
Very frequent (80-99%)HP:0001363
Depressed nasal root/bridge
Very frequent (80-99%)HP:0005280
Frontal protuberance
Very frequent (80-99%)HP:0002007
Hearing loss, conductive
Very frequent (80-99%)HP:0000405
Increased width of the forehead
Very frequent (80-99%)HP:0000337
Partial syndactyly
Very frequent (80-99%)HP:0006101
Small upper jaw
Very frequent (80-99%)HP:0000327
Syndactyly of feet
Very frequent (80-99%)HP:0001770
Abnormal semicircular canal morphology
Frequent (30-79%)HP:0011380
Abnormal spinal segmentation
Frequent (30-79%)HP:0003422
Absence of corpus callosum
Frequent (30-79%)HP:0001274
Absence of the septum pellucidum
Frequent (30-79%)HP:0001331
Angle class 3 malocclusion
Frequent (30-79%)HP:0000689
Aplastic/hypoplastic thumbs
Frequent (30-79%)HP:0009601
Broad thumbs
Frequent (30-79%)HP:0011304
Cervical C5/C6 vertebrae fusion
Frequent (30-79%)HP:0004635
Chronic middle ear infection
Frequent (30-79%)HP:0000389
Coanal stenosis
Frequent (30-79%)HP:0000452
Cryptorchidism
Frequent (30-79%)HP:0000028
Cutaneous syndactyly of digits
Frequent (30-79%)HP:0012725
Decreased volume of upper lip
Frequent (30-79%)HP:0000219

Quick Facts

SNOMED CT
205258009
UMLS CUI
C0001193
Fully Specified Name
Acrocephalosyndactyly type I (disorder)
Specialists
0
Diagnostic Biomarkers
0
HPO Phenotypes
30
Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Clinical content is derived from the SNOMED CT clinical ontology and curated medical knowledge graphs.