Signs & Symptoms
Based on Human Phenotype Ontology (HPO) disease-phenotype annotations.
Abnormal hands
Very frequent (80-99%)HP:0001155
Abnormality of the feet
Very frequent (80-99%)HP:0001760
Inflammatory abnormality of the skin
Very frequent (80-99%)HP:0011123
Keratoderma
Very frequent (80-99%)HP:0000982
Nonepidermolytic palmoplantar hyperkeratosis
Very frequent (80-99%)HP:0007404
Superficial dermal perivascular inflammatory infiltrate
Very frequent (80-99%)HP:0031190
Autoamputation
Frequent (30-79%)HP:0001218
Diffuse palmoplantar hyperkeratosis
Frequent (30-79%)HP:0007447
Erythema
Frequent (30-79%)HP:0010783
Flexion contractures
Frequent (30-79%)HP:0001371
Hyperhidrosis
Frequent (30-79%)HP:0000975
Hyperkeratosis with erythema
Frequent (30-79%)HP:0007390
Thickening of upper layer of skin
Frequent (30-79%)HP:0025092
Ichthyosiform abnormality of the skin
Occasional (5-29%)HP:0008064
Lichenoid skin lesion
Occasional (5-29%)HP:0031452
Brachydactyly
HP:0001156
Congenital symmetrical palmoplantar keratosis
HP:0007553
Fragile nails
HP:0001808
Perioral erythema
HP:0033194
Quick Facts
- SNOMED CT
- 239069005
- UMLS CUI
- C0025221
- Fully Specified Name
- Mal de Meleda (disorder)
- Specialists
- 0
- Diagnostic Biomarkers
- 0
- HPO Phenotypes
- 19
Medical Disclaimer
This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.
Clinical content is derived from the SNOMED CT clinical ontology and curated medical knowledge graphs.