Overview
Coats' disease is a disorder.
Auto-generated from clinical reference data. Not a substitute for medical advice.
Research Evidence
Peer-reviewed studies linked via MeSH term "Retinal Telangiectases" from the MEDLINE/PubMed database.
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Anti-Vascular Endothelial Growth Factor Treatment Outcomes in Macular Telangiectasia: A Systematic Review.
[object Object], [object Object], [object Object] et al. · Ophthalmologica · 2025
OCT angiography findings in type 2 macular telangiectasia: A meta-analysis.
[object Object], [object Object], [object Object] et al. · Indian J Ophthalmol · 2025
Efficacy and Safety of Anti-Vascular Endothelial Growth Factor Drugs for Coats' Disease Treatment: A Systematic Review.
[object Object], [object Object], [object Object] et al. · J Ocul Pharmacol Ther · 2023
PMID: 37504967Meta-Analysis
Treatment Modalities for Idiopathic Macular Telangiectasia: An Evidence-Based Systematic Review of the Literature.
[object Object], [object Object], [object Object] · Semin Ophthalmol · 2017
PMID: 27077639Meta-Analysis
Cell-Based Ciliary Neurotrophic Factor Therapy for Macular Telangiectasia Type 2.
[object Object], [object Object], [object Object] et al. · NEJM Evid · 2025
PMID: 40693847RCT
FUNCTIONAL AND STRUCTURAL EFFECTS OF NONDAMAGING RETINAL LASER THERAPY FOR MACULAR TELANGIECTASIA TYPE 2: A Randomized Sham-Controlled Clinical Trial.
[object Object], [object Object], [object Object] et al. · Retina · 2021
PMID: 33370517RCT
Ranibizumab for macular telangiectasia type 2 in the absence of subretinal neovascularization.
[object Object], [object Object], [object Object] et al. · Retina · 2014
PMID: 24978428RCT
Clinical histopathology and pathogenesis of macular telangiectasia type 2.
[object Object], [object Object], [object Object] et al. · Prog Retin Eye Res · 2026
International Consensuses and Guidelines on Diagnosing and Managing Coats Disease by the Academia Retina Internationalis (ARI), the Asia-Pacific Vitreo-retina Society (APVRS), and the Academy of the Asia-Pacific Professors of Ophthalmology (AAPPO).
[object Object], [object Object], [object Object] et al. · Am J Ophthalmol · 2026
PMID: 41110679Review
PATHOGENESIS, PROGNOSIS, AND SURGICAL OUTCOMES OF FULL-THICKNESS MACULAR HOLES IN MACULAR TELANGIECTASIA TYPE 2: A Literature Review.
[object Object], [object Object], [object Object] et al. · Retina · 2025
PMID: 39715562Review
Search all PubMed articles for Coats' disease
Research data from MEDLINE/PubMed
Signs & Symptoms
Based on Human Phenotype Ontology (HPO) disease-phenotype annotations.
Abnormality of retina blood vessels
Very frequent (80-99%)HP:0008046
Squint
Very frequent (80-99%)HP:0000486
Abnormality of the macula
Frequent (30-79%)HP:0001103
Glaucoma
Frequent (30-79%)HP:0000501
Retinal detachment
Frequent (30-79%)HP:0000541
Absent/small iris
Occasional (5-29%)HP:0008053
Anterior chamber anomalies
Occasional (5-29%)HP:0000593
Lens opacities
Occasional (5-29%)HP:0000518
Leukocoria
HP:0000555
Retinal telangiectasia
HP:0007763
Serous retinal detachment
HP:0012231
Related Conditions
Quick Facts
- SNOMED CT
- 360455002
- UMLS CUI
- C5964756
- Fully Specified Name
- Coats' disease (disorder)
- Specialists
- 0
- Diagnostic Biomarkers
- 0
- HPO Phenotypes
- 11
Medical Disclaimer
This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.
Clinical content is derived from the SNOMED CT clinical ontology and curated medical knowledge graphs.