Early-onset prion disease with prominent psychiatric features

disorder

SNOMED 784371009CUI C1864112

Overview

Early-onset prion disease with prominent psychiatric features is a disorder.

Auto-generated from clinical reference data. Not a substitute for medical advice.

Signs & Symptoms

Based on Human Phenotype Ontology (HPO) disease-phenotype annotations.

Choreiform movements

Very frequent (80-99%)HP:0002072

Behavioral symptoms

Frequent (30-79%)HP:0000708

Cognitive deficits

Frequent (30-79%)HP:0100543

Delusions

Frequent (30-79%)HP:0000746

Depressive episode

Frequent (30-79%)HP:0000716

Difficulty articulating speech

Frequent (30-79%)HP:0001260

Dilated cerebral ventricle

Frequent (30-79%)HP:0002119

Gait disturbance

Frequent (30-79%)HP:0001288

Inability to coordinate movements when walking

Frequent (30-79%)HP:0002066

Involuntary movements

Frequent (30-79%)HP:0004305

Progressive dementia

Frequent (30-79%)HP:0000726

Abnormal finger-nose-finger test

Occasional (5-29%)HP:0001310

Abnormal head movements

Occasional (5-29%)HP:0002457

Abnormal posturing

Occasional (5-29%)HP:0002533

Abnormality of mental function

Occasional (5-29%)HP:0011446

Abnormality of the basal ganglia

Occasional (5-29%)HP:0002134

Abnormality of the shoulder

Occasional (5-29%)HP:0003043

Cerebral cortex atrophy

Occasional (5-29%)HP:0002120

Clumsiness

Occasional (5-29%)HP:0002312

Decreased muscle movement

Occasional (5-29%)HP:0002375

Degeneration of cerebellum

Occasional (5-29%)HP:0001272

Delayed language development

Occasional (5-29%)HP:0000750

Electroencephalogram abnormal

Occasional (5-29%)HP:0002353

Epilepsy

Occasional (5-29%)HP:0001250

Excess astrocytes in brain

Occasional (5-29%)HP:0002171

Eye movement issue

Occasional (5-29%)HP:0000496

Fine motor skill dysfunction

Occasional (5-29%)HP:0007010

Frequent falls

Occasional (5-29%)HP:0002359

Generalised decreased muscle tone

Occasional (5-29%)HP:0001290

Hyperactive deep tendon reflexes

Occasional (5-29%)HP:0006801

Related Conditions

Autosomal dominant hereditary disorder(parent)

Huntington disease phenocopy syndrome(parent)

Cerebral degeneration(parent)

Hereditary degenerative disease of central nervous system(parent)

Quick Facts

SNOMED CT: 784371009
UMLS CUI: C1864112
Fully Specified Name: Huntington disease-like 1 (disorder)
Specialists: 0
Diagnostic Biomarkers: 0
HPO Phenotypes: 30

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Clinical content is derived from the SNOMED CT clinical ontology and curated medical knowledge graphs.