Overview
Hereditary factor XIII deficiency disease is a disorder.
Auto-generated from clinical reference data. Not a substitute for medical advice.
Research Evidence
Peer-reviewed studies linked via MeSH term "Factor XIII Deficiency" from the MEDLINE/PubMed database.
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Genotype pattern of factor V and XIII abnormalities in the Iranian population: A meta-analysis.
[object Object], [object Object], [object Object] et al. · Transfus Apher Sci · 2025
PMID: 40616960Meta-Analysis
Acquired Factor XIII Inhibitor in Hospitalized and Perioperative Patients: A Systematic Review of Case Reports and Case Series.
[object Object], [object Object], [object Object] et al. · Transfus Med Rev · 2016
PMID: 27167905Meta-Analysis
The burden and management of FXIII deficiency.
[object Object], [object Object], [object Object] et al. · Haemophilia · 2014
PMID: 25039531Meta-Analysis
Acquired FXIII inhibitors: a systematic review.
[object Object], [object Object], [object Object] et al. · J Thromb Thrombolysis · 2013
PMID: 23065324Meta-Analysis
Congenital factor XIII deficiency in women: a systematic review of literature.
[object Object], [object Object] · Haemophilia · 2013
PMID: 23992439Meta-Analysis
Factor XIII Deficiency: Laboratory, Molecular, and Clinical Aspects.
[object Object], [object Object], [object Object] · Semin Thromb Hemost · 2025
PMID: 39613144Review
Successful perinatal management of a woman with congenital factor XIII deficiency using recombinant factor XIII: A case report and literature review.
[object Object], [object Object], [object Object] et al. · J Obstet Gynaecol Res · 2024
PMID: 37875278Review
Traumatic intracranial hemorrhage in pediatrics: Implications of factor XIII deficiency and consumptive coagulopathy in abusive head trauma evaluation.
[object Object], [object Object], [object Object] et al. · Child Abuse Negl · 2024
PMID: 38325162Review
Abnormal bleeding after lumbar vertebrae surgery because of acquired factor XIII deficiency: A case report and literature review.
[object Object], [object Object], [object Object] · Medicine (Baltimore) · 2024
The role of factor XIII in patient blood management.
[object Object], [object Object], [object Object] · Blood Coagul Fibrinolysis · 2024
Search all PubMed articles for Hereditary factor XIII deficiency disease
Research data from MEDLINE/PubMed
Signs & Symptoms
Based on Human Phenotype Ontology (HPO) disease-phenotype annotations.
Abnormal umbilical stump bleeding
Very frequent (80-99%)HP:0011884
Reduced factor XIII activity
Very frequent (80-99%)HP:0008357
Umbilical cord hematoma
Very frequent (80-99%)HP:0030657
Bleeding below the skin
Frequent (30-79%)HP:0001933
Bruising susceptibility
Frequent (30-79%)HP:0000978
Cerebral hemorrhage
Frequent (30-79%)HP:0001342
Intramuscular haematoma
Frequent (30-79%)HP:0012233
Joint hemorrhage
Frequent (30-79%)HP:0005261
Oral cavity bleeding
Frequent (30-79%)HP:0030140
Spontaneous hematomas
Frequent (30-79%)HP:0007420
Bleeding gums
Occasional (5-29%)HP:0000225
Delayed onset bleeding
Occasional (5-29%)HP:0040232
Easy bleeding
Occasional (5-29%)HP:0011889
Ecchymosis
Occasional (5-29%)HP:0031364
Excessive bleeding after minor trauma
Occasional (5-29%)HP:0001934
Frequent nosebleeds
Occasional (5-29%)HP:0000421
Hypermenorrhea
Occasional (5-29%)HP:0000132
Poor wound healing
Occasional (5-29%)HP:0001058
Post-partum hemorrhage
Occasional (5-29%)HP:0011891
Prolonged bleeding after dental extraction
Occasional (5-29%)HP:0006298
Prolonged bleeding following circumcision
Occasional (5-29%)HP:0030137
Protracted bleeding after surgery
Occasional (5-29%)HP:0004846
Hepatic failure
Very rare (1-4%)HP:0001399
Inflammation of the large intestine
Very rare (1-4%)HP:0002037
Myeloid leukaemia
Very rare (1-4%)HP:0012324
Quick Facts
- SNOMED CT
- 50189006
- UMLS CUI
- C0015530
- Fully Specified Name
- Hereditary factor XIII deficiency disease (disorder)
- Specialists
- 0
- Diagnostic Biomarkers
- 0
- HPO Phenotypes
- 25
Medical Disclaimer
This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.
Clinical content is derived from the SNOMED CT clinical ontology and curated medical knowledge graphs.