Clinical Trials
2
Total Trials
1
Recruiting
1
With Results
Recent Trials
Albuminuria Lowering Effect of Dapagliflozin, Spironolactone and Their Combination in Adult Patients with Alport Syndrome (COMBINE-ALPORT)
NCT06499948Phase 4Recruiting34 enrolled
A Study of ELX-02 in Patients With Alport Syndrome
NCT05448755Phase 2Completed3 enrolled
Signs & Symptoms
Based on Human Phenotype Ontology (HPO) disease-phenotype annotations.
Blood in urine
Very frequent (80-99%)HP:0000790
Glomerular basement membrane lamellation
Very frequent (80-99%)HP:0030034
Thin glomerular basement membrane
Very frequent (80-99%)HP:0012577
High blood pressure
Frequent (30-79%)HP:0000822
Mesangial hypercellularity
Frequent (30-79%)HP:0012574
Proteinuria
Frequent (30-79%)HP:0000093
Renal failure in adulthood
Frequent (30-79%)HP:0000083
Abnormal corneal endothelium morphology
Occasional (5-29%)HP:0011488
Abnormal eye
Occasional (5-29%)HP:0000478
Anterior lenticonus
Occasional (5-29%)HP:0011501
C3 nephropathy
Occasional (5-29%)HP:0012576
End-stage renal disease
Occasional (5-29%)HP:0003774
Epithelial corneal erosions
Occasional (5-29%)HP:0000495
Focal and segmental glomerulosclerosis
Occasional (5-29%)HP:0000097
IgA deposition in the glomerulus
Occasional (5-29%)HP:0000794
Microhematuria
Occasional (5-29%)HP:0002907
Nephritis
Occasional (5-29%)HP:0000123
Nephrosis
Occasional (5-29%)HP:0000100
Renal glomerular foam cells
Occasional (5-29%)HP:0032583
Renal tubular cell atrophy
Occasional (5-29%)HP:0000092
Retinal flecks
Occasional (5-29%)HP:0012045
Sensorineural deafness
Occasional (5-29%)HP:0000407
Thickened glomerular basement membrane
Occasional (5-29%)HP:0004722
Thickening of glomerular capillary wall
Occasional (5-29%)HP:0025005
Tubulointerstitial renal fibrosis
Occasional (5-29%)HP:0005576
Abnormal aortic morphology
Very rare (1-4%)HP:0001679
Bronchitis, recurrent
Very rare (1-4%)HP:0002837
Bulge in wall of large artery that carries blood away from heart
Very rare (1-4%)HP:0004942
Coughing
Very rare (1-4%)HP:0012735
Deglutition disorder
Very rare (1-4%)HP:0002015
Related Conditions
Progressive hereditary glomerulonephritis without deafness(child)
Familial interstitial nephritis(child)
Hereditary diffuse mesangiocapillary glomerulonephritis(child)
Hereditary diffuse endocapillary proliferative glomerulonephritis(child)
Hereditary diffuse membranous glomerulonephritis(child)
Hereditary nephropathy co-occurrent with membranoproliferative glomerulonephritis type III(child)
Alport syndrome, intellectual disability, midface hypoplasia, elliptocytosis syndrome(child)
Microcephalus, glomerulonephritis, marfanoid habitus syndrome(child)
Nephrotic syndrome, deafness, pretibial epidermolysis bullosa syndrome(child)
Dense deposit disease(child)
Collagen IV nephropathy(child)
Glomerulonephritis(parent)
Hereditary nephropathy(parent)
Genetic disease of glomerulus(parent)
Quick Facts
- SNOMED CT
- 399340005
- UMLS CUI
- C0027706
- Fully Specified Name
- Hereditary nephritis (disorder)
- Specialists
- 0
- Diagnostic Biomarkers
- 0
- HPO Phenotypes
- 30
- Clinical Trials
- 2
Medical Disclaimer
This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.
Clinical content is derived from the SNOMED CT clinical ontology and curated medical knowledge graphs.