Overview
Ichthyosis hystrix of Curth-Macklin is a disorder.
Auto-generated from clinical reference data. Not a substitute for medical advice.
Signs & Symptoms
Based on Human Phenotype Ontology (HPO) disease-phenotype annotations.
Dorsal dupuytren nodules
Always present (100%)HP:0032541
Hyperkeratotic papule
Always present (100%)HP:0045059
Keratoderma
Always present (100%)HP:0000982
Diffuse palmoplantar hyperkeratosis
Very frequent (80-99%)HP:0007447
Epidermal hyperkeratosis
Very frequent (80-99%)HP:0000962
Ichthyosiform abnormality of the skin
Very frequent (80-99%)HP:0008064
Skin infections, recurrent
Very frequent (80-99%)HP:0001581
Dystrophic nails
Frequent (30-79%)HP:0008404
Flexion contractures
Frequent (30-79%)HP:0001371
Pseudoainhum
Frequent (30-79%)HP:0009775
Autoamputation of digits
Occasional (5-29%)HP:0007460
Easy bleeding
Occasional (5-29%)HP:0011889
Fragile skin
Excluded (<1%)HP:0001030
Scaling skin
Excluded (<1%)HP:0040189
Skin bullae
Excluded (<1%)HP:0008066
Related Conditions
Quick Facts
- SNOMED CT
- 254170001
- UMLS CUI
- C1840296
- Fully Specified Name
- Ichthyosis hystrix of Curth-Macklin (disorder)
- Specialists
- 0
- Diagnostic Biomarkers
- 0
- HPO Phenotypes
- 15
Medical Disclaimer
This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.
Clinical content is derived from the SNOMED CT clinical ontology and curated medical knowledge graphs.