Isolated thyrotropin deficiency

disorder

SNOMED 89261000CUI C4082174

Overview

Source: MedlinePlus.gov, National Library of Medicine. Not a substitute for medical advice.

Signs & Symptoms

Based on Human Phenotype Ontology (HPO) disease-phenotype annotations.

Hypothyroidism

Always present (100%)HP:0000821

Abnormal circulating thyroglobulin concentration

Very frequent (80-99%)HP:0025483

Decreased circulating T4 concentration

Very frequent (80-99%)HP:0031507

Decreased thyrotropin level

Very frequent (80-99%)HP:0031098

Increased pituitary glycoprotein hormone alpha subunit level

Very frequent (80-99%)HP:0031208

Reduced radioactive iodine uptake

Very frequent (80-99%)HP:0031219

Small thyroid gland

Very frequent (80-99%)HP:0005990

TSH deficient hypothyroidism

Very frequent (80-99%)HP:0008245

Anomaly of the epiphyses

Frequent (30-79%)HP:0005930

Constipation

Frequent (30-79%)HP:0002019

Delayed closure of the fontanelles

Frequent (30-79%)HP:0000270

Delayed motor milestones

Frequent (30-79%)HP:0001270

Delayed ossification proximal femoral epiphyses

Frequent (30-79%)HP:0008828

Delayed skeletal development

Frequent (30-79%)HP:0002750

Dry skin

Frequent (30-79%)HP:0000958

Elevated serum cholesterol

Frequent (30-79%)HP:0003124

Facial swelling

Frequent (30-79%)HP:0000282

Feeding difficulties

Frequent (30-79%)HP:0011968

Feeding difficulties in infancy

Frequent (30-79%)HP:0008872

Flat nasal bridge

Frequent (30-79%)HP:0005280

Growth deficiency

Frequent (30-79%)HP:0001510

Hoarse cry

Frequent (30-79%)HP:0001615

Husky voice

Frequent (30-79%)HP:0001609

Hyperbilirubinemia, neonatal

Frequent (30-79%)HP:0003265

Hyperplasia of hypophysial fossa

Frequent (30-79%)HP:0002690

Hyporeflexia

Frequent (30-79%)HP:0001265

Hypothermia

Frequent (30-79%)HP:0002045

Large posterior fontanelle

Frequent (30-79%)HP:0004491

Large testis

Frequent (30-79%)HP:0000053

Lingual hyperplasia

Frequent (30-79%)HP:0000158

Related Conditions

Secondary hypothyroidism(parent)

Quick Facts

SNOMED CT: 89261000
UMLS CUI: C4082174
Fully Specified Name: Isolated thyrotropin deficiency (disorder)
Specialists: 0
Diagnostic Biomarkers: 0
HPO Phenotypes: 30

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Clinical content is derived from the SNOMED CT clinical ontology and curated medical knowledge graphs.