Leprosy

disorder

SNOMED 81004002CUI C0023343

Overview

Source: MedlinePlus.gov, National Library of Medicine. Not a substitute for medical advice.

Treatments & Interventions

Thalidomide

substance

Rifampin

substance

Research Evidence

Peer-reviewed studies linked via MeSH term "Leprosy" from the MEDLINE/PubMed database.

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Leprosy relapse after multidrug therapy: Systematic review and meta-analysis.

[object Object], [object Object], [object Object] et al. · PLoS Negl Trop Dis · 2025

PMID: 41082563Meta-AnalysisFull text (PMC)

Techniques for the surgical correction of lagophthalmos secondary to leprosy: A systematic review.

[object Object], [object Object], [object Object] et al. · PLoS Negl Trop Dis · 2025

PMID: 40522996Meta-AnalysisFull text (PMC)

On the usage of artificial intelligence in leprosy care: A systematic literature review.

[object Object], [object Object], [object Object] et al. · PLoS Comput Biol · 2025

PMID: 40570262Meta-AnalysisFull text (PMC)

Factors associated with the spatial distribution of leprosy: a systematic review of the published literature.

[object Object], [object Object], [object Object] et al. · Geospat Health · 2025

PMID: 40964901Meta-Analysis

Association of dermatological manifestations with in fertility: A systematic review of literature.

[object Object], [object Object], [object Object] et al. · J Pak Med Assoc · 2025

PMID: 41378403Meta-Analysis

Leprosy in skeletons from archaeological sites: A systematic review.

[object Object], [object Object], [object Object] et al. · PLoS Negl Trop Dis · 2025

PMID: 40828789Meta-AnalysisFull text (PMC)

Cranial nerve palsies in leprosy: a systematic review of published case reports and case series.

[object Object], [object Object], [object Object] et al. · Acta Neurol Belg · 2025

PMID: 39322926Meta-Analysis

Nutritional Status in Leprosy Patients: A Systematic Review and Meta-analysis.

[object Object], [object Object] · Infect Disord Drug Targets · 2024

PMID: 37990432Meta-Analysis

The spectrum of central nervous system manifestations in leprosy: a systematic review of published case reports and case series.

[object Object], [object Object], [object Object] et al. · Trans R Soc Trop Med Hyg · 2024

PMID: 37850518Meta-Analysis

Self-healing in leprosy: A systematic review.

[object Object], [object Object], [object Object] et al. · PLoS Negl Trop Dis · 2024

PMID: 39264863Meta-AnalysisFull text (PMC)

Search all PubMed articles for Leprosy

Research data from MEDLINE/PubMed

Signs & Symptoms

Based on Human Phenotype Ontology (HPO) disease-phenotype annotations.

Peripheral neuropathy

Very frequent (80-99%)HP:0009830

Acral ulceration

Frequent (30-79%)HP:0006121

Acute episodes of neuropathic symptoms

Frequent (30-79%)HP:0003489

Anti-sphingolipid antibody positivity

Frequent (30-79%)HP:0034102

Autonomic dysregulation

Frequent (30-79%)HP:0012332

Dissociated sensory loss

Frequent (30-79%)HP:0010835

Enlarged peripheral nerve

Frequent (30-79%)HP:0012645

Entrapment neuropathy

Frequent (30-79%)HP:0012181

Epidermal hyperkeratosis

Frequent (30-79%)HP:0000962

Growth of abnormal tissue on or under the skin

Frequent (30-79%)HP:0200036

Hypohidrosis

Frequent (30-79%)HP:0000966

Hypopigmented macule

Frequent (30-79%)HP:0020073

Impaired thermal sensitivity

Frequent (30-79%)HP:0010829

Neurogenic muscle atrophy, especially in the lower limbs

Frequent (30-79%)HP:0003202

Paresthesia

Frequent (30-79%)HP:0003401

Sparse body hair

Frequent (30-79%)HP:0002231

Abnormality of the facial nerve

Occasional (5-29%)HP:0010827

Abnormality of the upper respiratory tract

Occasional (5-29%)HP:0002087

Anomaly of facial skeleton

Occasional (5-29%)HP:0011821

Aplasia of eyebrows

Occasional (5-29%)HP:0002223

Autoamputation of digits

Occasional (5-29%)HP:0007460

Carpal tunnel syndrome

Occasional (5-29%)HP:0012185

Ciliary Madarosis

Occasional (5-29%)HP:0011457

Corneal ulcerations

Occasional (5-29%)HP:0012804

Decreased corneal sensitivity

Occasional (5-29%)HP:0012155

Dysesthesia

Occasional (5-29%)HP:0012534

Facial shape compression

Occasional (5-29%)HP:0011334

Hair loss

Occasional (5-29%)HP:0001596

Inability to heel walk

Occasional (5-29%)HP:0009027

Muscle weakness

Occasional (5-29%)HP:0001324

Related Conditions

RR - Leprosy reversal reaction(child)

Leprosy neuropathy(child)

Indeterminate leprosy(child)

Lepromatous leprosy(child)

Tuberculoid leprosy(child)

Leontiasis(child)

Type 1 lepra reaction(child)

Borderline leprosy(child)

Dapsone resistant leprosy(child)

Paucibacillary leprosy(child)

Multibacillary leprosy(child)

Arthritis caused by Mycobacterium leprae(child)

Infection of eyelid caused by Mycobacterium leprae(child)

Mycobacterium leprae dacryoadenitis(child)

Gingival disease caused by Mycobacterium leprae(child)

Leprosy xerosis cutis(child)

Mycobacteriosis(parent)

Quick Facts

SNOMED CT: 81004002
UMLS CUI: C0023343
Fully Specified Name: Leprosy (disorder)
Specialists: 0
Diagnostic Biomarkers: 0
HPO Phenotypes: 30
Known Treatments: 2

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Clinical content is derived from the SNOMED CT clinical ontology and curated medical knowledge graphs.