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Mucopolysaccharidosis, MPS-VII

disorder
SNOMED 43916004CUI C0085132

Overview

Source: MedlinePlus.gov, National Library of Medicine. Not a substitute for medical advice.

Signs & Symptoms

Based on Human Phenotype Ontology (HPO) disease-phenotype annotations.

Abdominal protuberance
Always present (100%)HP:0001538
Beta-glucuronidase low in leukocytes
Always present (100%)HP:0034859
Delayed motor milestones
Always present (100%)HP:0001270
Early bone maturation
Always present (100%)HP:0005616
Gap between large left and right abdominal muscles
Always present (100%)HP:0001540
Growth delay as children
Always present (100%)HP:0008897
Large iliac wings
Always present (100%)HP:0008818
Palpebronasal fold
Always present (100%)HP:0000286
Pectus excavatum
Always present (100%)HP:0000767
Short stature, severe
Always present (100%)HP:0003510
Spatulate ribs
Always present (100%)HP:0012307
Unbalanced face
Always present (100%)HP:0000324
Urinary glycosaminoglycan excretion
Always present (100%)HP:0003541
Abnormal pleura morphology
Very frequent (80-99%)HP:0002103
Anterior beaking of lower thoracic vertebrae
Very frequent (80-99%)HP:0004607
Big calvaria
Very frequent (80-99%)HP:0000256
Cobb angle greater than ten degrees
Very frequent (80-99%)HP:0002650
Decreased body height
Very frequent (80-99%)HP:0004322
Dysostosis multiplex
Very frequent (80-99%)HP:0000943
Flat facial shape
Very frequent (80-99%)HP:0012368
Flexion contractures
Very frequent (80-99%)HP:0001371
Inguinal hernia
Very frequent (80-99%)HP:0000023
Limitation of joint mobility
Very frequent (80-99%)HP:0001376
Lymphatic obstruction
Very frequent (80-99%)HP:0001004
Mental deficiency
Very frequent (80-99%)HP:0001249
Peritoneal effusion
Very frequent (80-99%)HP:0001541
respiratory infections, recurrent
Very frequent (80-99%)HP:0002205
Scarring or clouding of the cornea of the eye
Very frequent (80-99%)HP:0007957
Thickened facial skin with coarse facial features
Very frequent (80-99%)HP:0000280
Thickening of shaft or central part of long bones
Very frequent (80-99%)HP:0005019

Quick Facts

SNOMED CT
43916004
UMLS CUI
C0085132
Fully Specified Name
Mucopolysaccharidosis type VII (disorder)
Specialists
0
Diagnostic Biomarkers
0
HPO Phenotypes
30
Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Clinical content is derived from the SNOMED CT clinical ontology and curated medical knowledge graphs.