Multicentric osteolysis nodulosis arthropathy spectrum

disorder

SNOMED 716868003CUI C1850155

Overview

Multicentric osteolysis nodulosis arthropathy spectrum is a disorder.

Auto-generated from clinical reference data. Not a substitute for medical advice.

Signs & Symptoms

Based on Human Phenotype Ontology (HPO) disease-phenotype annotations.

Arthritic pain

Always present (100%)HP:0002829

Broad shaft of long bone of hand

Always present (100%)HP:0006012

Bulbous nasal tip

Always present (100%)HP:0000414

Gait disturbance

Always present (100%)HP:0001288

Interphalangeal joint erosions

Always present (100%)HP:0006252

Interphalangeal joint flexion contractures

Always present (100%)HP:0001220

Metacarpal osteolysis

Always present (100%)HP:0001504

Metatarsal osteolysis

Always present (100%)HP:0001473

Thickened facial skin with coarse facial features

Always present (100%)HP:0000280

Thin cortices

Always present (100%)HP:0002753

Thin metacarpal cortices

Always present (100%)HP:0006086

Thin metatarsal cortices

Always present (100%)HP:0008078

Wide long bone of foot

Always present (100%)HP:0001783

Widened metaphyses

Always present (100%)HP:0003016

Abnormal shape of hand

Very frequent (80-99%)HP:0005922

Breakdown of bone

Very frequent (80-99%)HP:0002797

Carpal bone osteolysis

Very frequent (80-99%)HP:0001495

Disease of the joints

Very frequent (80-99%)HP:0003040

Distortion of face

Very frequent (80-99%)HP:0001999

Gingival hyperplasia

Very frequent (80-99%)HP:0000212

Hirsutism

Very frequent (80-99%)HP:0001007

Joint inflammation

Very frequent (80-99%)HP:0001369

Osteolysis involving bones of the lower limbs

Very frequent (80-99%)HP:0009139

Osteolysis involving bones of the upper limbs

Very frequent (80-99%)HP:0045039

Osteopenia

Very frequent (80-99%)HP:0000938

Osteoporosis

Very frequent (80-99%)HP:0000939

Tarsal bone osteolysis

Very frequent (80-99%)HP:0006234

Abnormal vertebral bodies

Frequent (30-79%)HP:0003312

Broad collarbone

Frequent (30-79%)HP:0000916

C1-C2 subluxation

Frequent (30-79%)HP:0003320

Related Conditions

Multiple malformation syndrome with facial-limb defects as major feature(parent)

Recessive hereditary disorder (autosomal)(parent)

Osteolysis(parent)

Hereditary disorder of musculoskeletal system(parent)

Congenital anomaly of skeletal bone(parent)

Developmental hereditary disorder(parent)

Quick Facts

SNOMED CT: 716868003
UMLS CUI: C1850155
Fully Specified Name: Multicentric osteolysis nodulosis arthropathy spectrum (disorder)
Specialists: 0
Diagnostic Biomarkers: 0
HPO Phenotypes: 30

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Clinical content is derived from the SNOMED CT clinical ontology and curated medical knowledge graphs.