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Nail-patella syndrome

disorder
SNOMED 22199006CUI C0027341

Overview

Source: MedlinePlus.gov, National Library of Medicine. Not a substitute for medical advice.

Research Evidence

Peer-reviewed studies linked via MeSH term "Syndrome, Nail-Patella" from the MEDLINE/PubMed database.

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[Translated article] Congenital and Hereditary Nail Disease.
[object Object], [object Object], [object Object] et al. · Actas Dermosifiliogr · 2024
PMID: 38972583Review
The limb dorsoventral axis: Lmx1b's role in development, pathology, evolution, and regeneration.
[object Object], [object Object], [object Object] et al. · Dev Dyn · 2024
PMID: 38288855ReviewFull text (PMC)
AJKD Atlas of Renal Pathology: Nail-Patella Syndrome-Associated Nephropathy.
[object Object], [object Object], [object Object] et al. · Am J Kidney Dis · 2017
PMID: 28941488Review
Nail-patella syndrome.
[object Object] · Pflugers Arch · 2017
PMID: 28681095Review
Spectrum of LMX1B mutations: from nail-patella syndrome to isolated nephropathy.
[object Object], [object Object], [object Object] et al. · Pediatr Nephrol · 2017
PMID: 27450397Review
Iliac "horns".
[object Object], [object Object] · Abdom Radiol (NY) · 2017
PMID: 28612165Review
The spectrum of nephrocutaneous diseases and associations: Genetic causes of nephrocutaneous disease.
[object Object], [object Object], [object Object] et al. · J Am Acad Dermatol · 2016
PMID: 26775773Review
Tips to diagnose uncommon nail disorders.
[object Object], [object Object] · Dermatol Clin · 2015
PMID: 25828712Review
[Alterations in nails and teeth as a clue for genodermatoses].
[object Object] · Hautarzt · 2014
PMID: 24898505Review
Collagen Type III Glomerulopathies.
[object Object] · Adv Chronic Kidney Dis · 2012
PMID: 22449347Review

Signs & Symptoms

Based on Human Phenotype Ontology (HPO) disease-phenotype annotations.

Abnormality of digit
Very frequent (80-99%)HP:0011297
Aplasia of the distal interphalangeal creases
Very frequent (80-99%)HP:0001032
Nail disease
Very frequent (80-99%)HP:0001597
Abnormal gastrointestinal tract morphology
Frequent (30-79%)HP:0012718
Abnormal iris pigmentation
Frequent (30-79%)HP:0008034
Abnormality of the elbow
Frequent (30-79%)HP:0009811
Abnormality of the knee
Frequent (30-79%)HP:0002815
Arthritis
Frequent (30-79%)HP:0001369
Back pain
Frequent (30-79%)HP:0003418
Decreased muscle mass
Frequent (30-79%)HP:0003199
Dropped arches
Frequent (30-79%)HP:0001763
Dyschezia
Frequent (30-79%)HP:0002019
Dysplastic fingernails
Frequent (30-79%)HP:0100798
Equinovarus deformity
Frequent (30-79%)HP:0008110
Fixed flexion at the elbow joint
Frequent (30-79%)HP:0002987
Flexion contractures
Frequent (30-79%)HP:0001371
Iliac horns
Frequent (30-79%)HP:0009780
Renal anomalies
Frequent (30-79%)HP:0000077
Abnormal cranial nerve physiology
Occasional (5-29%)HP:0031910
Abnormal kneecap
Occasional (5-29%)HP:0003045
Abnormal tibia morphology
Occasional (5-29%)HP:0002992
Abnormal toenail development
Occasional (5-29%)HP:0100797
Abnormality of the thighbone
Occasional (5-29%)HP:0002823
Achilles tendon contracture
Occasional (5-29%)HP:0001771
Acroparesthesia
Occasional (5-29%)HP:0031006
Bilateral fifth digit clinodactyly
Occasional (5-29%)HP:0004209
Blood in urine
Occasional (5-29%)HP:0000790
Contracture of the distal interphalangeal joint of the fingers
Occasional (5-29%)HP:0009697
Decreased bone mineral density Z score
Occasional (5-29%)HP:0004349
Dislocated patellae
Occasional (5-29%)HP:0002999

Quick Facts

SNOMED CT
22199006
UMLS CUI
C0027341
Fully Specified Name
Nail-patella syndrome (disorder)
Specialists
0
Diagnostic Biomarkers
0
HPO Phenotypes
30
Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Clinical content is derived from the SNOMED CT clinical ontology and curated medical knowledge graphs.