Research Evidence
Peer-reviewed studies linked via MeSH term "Necrobiosis Lipoidica" from the MEDLINE/PubMed database.
Sort:
Treatment options for necrobiosis lipoidica: a systematic review.
[object Object], [object Object], [object Object] et al. · Int J Dermatol · 2023
PMID: 37772666Meta-Analysis
Use of Janus kinase inhibitors for granulomatous dermatoses: A systematic review.
[object Object], [object Object], [object Object] et al. · J Am Acad Dermatol · 2023
PMID: 36990321Meta-Analysis
Specific skin signs as a cutaneous marker of diabetes mellitus and the prediabetic state - a systematic review.
[object Object], [object Object], [object Object] et al. · Dan Med J · 2017
PMID: 28007053Meta-Analysis
A systematic review of the relationship between glycemic control and necrobiosis lipoidica diabeticorum in patients with diabetes mellitus.
[object Object], [object Object], [object Object] et al. · Int J Dermatol · 2017
PMID: 28650076Meta-Analysis
Cofactors and comorbidities of necrobiosis lipoidica: analysis of the German DRG data from 2012.
[object Object], [object Object], [object Object] et al. · J Dtsch Dermatol Ges · 2016
PMID: 26972191Meta-Analysis
Ultraviolet A phototherapy for sclerotic skin diseases: a systematic review.
[object Object], [object Object], [object Object] et al. · J Am Acad Dermatol · 2008
PMID: 18835066Meta-Analysis
Cutaneous manifestations of diabetes mellitus: a narrative review.
[object Object], [object Object], [object Object] et al. · Einstein (Sao Paulo) · 2025
A Breakthrough in the Treatment of Necrobiosis Lipoidica? Update on Treatment, Etiopathogenesis, Diagnosis, and Clinical Presentation.
[object Object], [object Object], [object Object] et al. · Int J Mol Sci · 2024
Skin Involvement in Paediatric Patients with Type 1 Diabetes.
[object Object], [object Object], [object Object] · Curr Diabetes Rev · 2022
PMID: 34477525Review
Laser and light therapies for the treatment of necrobiosis lipoidica.
[object Object], [object Object], [object Object] et al. · Lasers Med Sci · 2021
PMID: 32970197Review
Search all PubMed articles for Necrobiosis lipoidica
Research data from MEDLINE/PubMed
Signs & Symptoms
Based on Human Phenotype Ontology (HPO) disease-phenotype annotations.
Annular cutaneous lesion
Very frequent (80-99%)HP:0025528
Inflammatory abnormality of the skin
Very frequent (80-99%)HP:0011123
Abnormality of neutrophil physiology
Frequent (30-79%)HP:0011990
Abnormality of the lower limb
Frequent (30-79%)HP:0002814
Diabetes mellitus
Frequent (30-79%)HP:0000819
Erythema
Frequent (30-79%)HP:0010783
Fragile skin
Frequent (30-79%)HP:0001030
Granuloma
Frequent (30-79%)HP:0032252
Growth of abnormal tissue on or under the skin
Frequent (30-79%)HP:0200036
Indurated nodule
Frequent (30-79%)HP:0032217
Open skin sore
Frequent (30-79%)HP:0200042
Papules
Frequent (30-79%)HP:0200034
Skin plaque
Frequent (30-79%)HP:0200035
Teleangiectasia of the skin
Frequent (30-79%)HP:0100585
Thin, atrophic scars
Frequent (30-79%)HP:0001075
Abnormal forearm morphology
Occasional (5-29%)HP:0002973
Abnormal hands
Occasional (5-29%)HP:0001155
Anomaly of scalp
Occasional (5-29%)HP:0001965
Disorder of face
Occasional (5-29%)HP:0000271
Abnormality of the thyroid gland
Very rare (1-4%)HP:0000820
Squamous cell carcinoma
Very rare (1-4%)HP:0002860
Related Conditions
Necrobiosis lipoidica, necrobiotic type(child)
Granulomatosis disciformis et progressiva(child)
Necrobiosis lipoidica diabeticorum(child)
Necrobiosis lipoidica, granulomatous type(child)
Granulomatous disorder of the skin and subcutaneous tissue(parent)
Chronic inflammatory disease(parent)
Soft tissue lesion(parent)
Degenerative disorder(parent)
Injury of integument(parent)
Soft tissue injury(parent)
Tissue necrosis(parent)
Quick Facts
- SNOMED CT
- 9418005
- UMLS CUI
- C0027538
- Fully Specified Name
- Necrobiosis lipoidica (disorder)
- Specialists
- 0
- Diagnostic Biomarkers
- 0
- HPO Phenotypes
- 21
Medical Disclaimer
This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.
Clinical content is derived from the SNOMED CT clinical ontology and curated medical knowledge graphs.