Nephroblastoma

disorder

SNOMED 302849000CUI C0027708

Overview

Source: MedlinePlus.gov, National Library of Medicine. Not a substitute for medical advice.

Treatments & Interventions

Doxorubicin hydrochloride

substance

Doxorubicin

substance

Vincristine

substance

Dactinomycin

substance

Vincristine sulphate

substance

Daunorubicin hydrochloride liposome

substance

Doxorubicin hydrochloride pegylated liposome

substance

Clinical Trials

Total Trials

Recruiting

With Results

Recent Trials

A Study of Combination Chemotherapy for Patients With Newly Diagnosed DAWT and Relapsed FHWT

NCT04322318Phase 2Recruiting256 enrolled

Tegavivint for the Treatment of Recurrent or Refractory Solid Tumors, Including Lymphomas and Desmoid Tumors

NCT04851119Phase 1/PHASE2Recruiting147 enrolled

Vincristine, Dactinomycin, and Doxorubicin With or Without Radiation Therapy or Observation Only in Treating Younger Patients Who Are Undergoing Surgery for Newly Diagnosed Stage I, Stage II, or Stage III Wilms' Tumor

NCT00352534Phase 3Active Not Recruiting808 enrolled

Ensartinib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With ALK or ROS1 Genomic Alterations (A Pediatric MATCH Treatment Trial)

NCT03213652Phase 2Active Not Recruiting13 enrolled

Efficacy of Prophylactic Itraconazole in High-Dose Chemotherapy and Autologous Hematopoietic Stem Cell Transplantation

NCT00336531Phase 4Completed100 enrolled

View all 5 trials on ClinicalTrials.gov

Signs & Symptoms

Based on Human Phenotype Ontology (HPO) disease-phenotype annotations.

Abdominal mass

Very frequent (80-99%)HP:0031500

Abnormal tissue mass

Very frequent (80-99%)HP:0002664

Nephroblastoma

Very frequent (80-99%)HP:0002667

Abdominal discomfort

Frequent (30-79%)HP:0002027

Duplication of renal pelvis

Frequent (30-79%)HP:0005580

Macroscopic hematuria

Frequent (30-79%)HP:0012587

Abnormal uterus morphology

Occasional (5-29%)HP:0031105

Aniridia

Occasional (5-29%)HP:0000526

Cryptorchidism

Occasional (5-29%)HP:0000028

Decreased haemoglobin

Occasional (5-29%)HP:0001903

Ectopic kidney

Occasional (5-29%)HP:0000086

Fused kidneys

Occasional (5-29%)HP:0000085

Hemihypertrophy

Occasional (5-29%)HP:0001528

High blood pressure

Occasional (5-29%)HP:0000822

Hypercalcemia

Occasional (5-29%)HP:0003072

Hypospadias

Occasional (5-29%)HP:0000047

Liver cancer

Occasional (5-29%)HP:0002896

Lung cancer

Occasional (5-29%)HP:0100526

Lymph node hyperplasia

Occasional (5-29%)HP:0002716

Malaise

Occasional (5-29%)HP:0033834

Microhematuria

Occasional (5-29%)HP:0002907

Polyglobulia

Occasional (5-29%)HP:0001901

Pyrexia

Occasional (5-29%)HP:0001945

Reduced von Willebrand factor activity

Occasional (5-29%)HP:0008330

Varicocele

Occasional (5-29%)HP:0012871

Weight loss

Occasional (5-29%)HP:0001824

Difficulty breathing

Very rare (1-4%)HP:0002094

Related Conditions

GLOW syndrome(child)

Nephroblastoma of left kidney(child)

Nephroblastoma of right kidney(child)

Primary Wilms tumour(child)

Malignant neoplasm of kidney parenchyma(parent)

Quick Facts

SNOMED CT: 302849000
UMLS CUI: C0027708
Fully Specified Name: Nephroblastoma (disorder)
Specialists: 0
Diagnostic Biomarkers: 0
HPO Phenotypes: 27
Known Treatments: 7
Clinical Trials: 5

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Clinical content is derived from the SNOMED CT clinical ontology and curated medical knowledge graphs.