Nezelof's syndrome

disorder

SNOMED 55602000CUI C0152094

Overview

Nezelof's syndrome is a disorder.

Auto-generated from clinical reference data. Not a substitute for medical advice.

Signs & Symptoms

Based on Human Phenotype Ontology (HPO) disease-phenotype annotations.

Abnormally low T cell receptor excision circle level

Always present (100%)HP:0031545

Athymia

Always present (100%)HP:0005359

Recurrent viral infections

Always present (100%)HP:0004429

Cellular immunodeficiency

Very frequent (80-99%)HP:0005374

Decreased mitogen-induced T-cell proliferation

Very frequent (80-99%)HP:0031381

Decreased proportion of naive T cells

Very frequent (80-99%)HP:0031397

Predisposition to infections

Very frequent (80-99%)HP:0002719

Reduced number of T cells

Very frequent (80-99%)HP:0005403

Severe T-cell immunodeficiency

Very frequent (80-99%)HP:0005352

Autoimmunity

Frequent (30-79%)HP:0002960

Gastrointestinal infections

Frequent (30-79%)HP:0004798

Opportunistic infection

Frequent (30-79%)HP:0031690

Pneumonia

Frequent (30-79%)HP:0002090

Prone to bacterial infection

Frequent (30-79%)HP:0002718

Severe viral infection

Frequent (30-79%)HP:0031691

Undergrowth

Frequent (30-79%)HP:0001508

Unusual course of infection

Frequent (30-79%)HP:0032169

Atypical or prolonged hepatitis

Occasional (5-29%)HP:0200122

Chronic middle ear infection

Occasional (5-29%)HP:0000389

Chronic oral thrush

Occasional (5-29%)HP:0009098

Combined immunodeficiency

Occasional (5-29%)HP:0005387

Dermatitis

Occasional (5-29%)HP:0000964

Diarrhea

Occasional (5-29%)HP:0002014

Direct Coombs positive

Occasional (5-29%)HP:0004844

Hypocalcemic tetany

Occasional (5-29%)HP:0003472

Hypothyroidism

Occasional (5-29%)HP:0000821

Infection in blood stream

Occasional (5-29%)HP:0100806

Intestinal malabsorption

Occasional (5-29%)HP:0002024

Invasive fungal infection

Occasional (5-29%)HP:0020101

Lymph node hyperplasia

Occasional (5-29%)HP:0002716

Related Conditions

Severe combined immunodeficiency disease(parent)

Quick Facts

SNOMED CT: 55602000
UMLS CUI: C0152094
Fully Specified Name: Nezelof's syndrome (disorder)
Specialists: 0
Diagnostic Biomarkers: 0
HPO Phenotypes: 30

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Clinical content is derived from the SNOMED CT clinical ontology and curated medical knowledge graphs.