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Osteogenesis imperfecta, perinatal lethal

disorder
SNOMED 205496008CUI C0268358

Overview

Source: MedlinePlus.gov, National Library of Medicine. Not a substitute for medical advice.

Signs & Symptoms

Based on Human Phenotype Ontology (HPO) disease-phenotype annotations.

Absent bone maturation of skullcap
Always present (100%)HP:0005623
Bell-shaped chest
Always present (100%)HP:0001591
Crumpled long bones
Always present (100%)HP:0006367
Multiple prenatal fractures
Always present (100%)HP:0005855
Multiple rib fractures
Always present (100%)HP:0006640
Short limbs
Always present (100%)HP:0009826
Slender ribs
Always present (100%)HP:0000883
Thoracic hypoplasia
Always present (100%)HP:0005257
Abnormality of pelvic girdle bone morphology
HP:0002644
Birth weight less than 10th percentile
HP:0001518
Cardiac insufficiency
HP:0001635
Dwarfism, short-limbed
HP:0008873
Extra bones within cranial sutures
HP:0002645
Flattened vertebral bodies
HP:0000926
Frequent fractures
HP:0002757
Grey sclerae
HP:0000592
Hooked nose
HP:0000444
Large, late-closing fontanelle
HP:0000239
Nonimmune hydrops fetalis
HP:0001790
Premature birth
HP:0001622
Puolmonary valve insufficiency
HP:0010444
Respiratory insufficiency
HP:0002093
Thin skin
HP:0000963
Tibial bowing
HP:0002982
Widened long bones
HP:0005622

Quick Facts

SNOMED CT
205496008
UMLS CUI
C0268358
Fully Specified Name
Osteogenesis imperfecta type II (disorder)
Specialists
0
Diagnostic Biomarkers
0
HPO Phenotypes
25
Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Clinical content is derived from the SNOMED CT clinical ontology and curated medical knowledge graphs.