Pachydermoperiostosis syndrome

disorder

SNOMED 88220006CUI C0029411

Overview

Source: MedlinePlus.gov, National Library of Medicine. Not a substitute for medical advice.

Research Evidence

Peer-reviewed studies linked via MeSH term "Osteoarthropathy, Primary Hypertrophic" from the MEDLINE/PubMed database.

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Exogenous lipoid pneumonia in children: A systematic review.

[object Object], [object Object], [object Object] et al. · Paediatr Respir Rev · 2020

PMID: 30962152Meta-AnalysisFull text (PMC)

Effectiveness of non-steroidal anti-inflammatory drugs among patients with primary hypertrophic osteoarthropathy: A systematic review.

[object Object], [object Object], [object Object] et al. · J Dermatol Sci · 2018

PMID: 29305259Meta-Analysis

Genotype and phenotype characterization of primary hypertrophic osteoarthropathy type 2 and chronic enteropathy associated with SLCO2A1: Report of two cases and literature review.

[object Object], [object Object], [object Object] et al. · Am J Med Genet A · 2024

PMID: 37915296Review

Primary hypertrophic osteoarthropathy: genetics, clinical features and management.

[object Object], [object Object], [object Object] et al. · Front Endocrinol (Lausanne) · 2023

PMID: 37705574ReviewFull text (PMC)

Juvenile Disease Processes Affecting the Forelimb in Canines.

[object Object] · Vet Clin North Am Small Anim Pract · 2021

PMID: 33558013Review

Hypertrophic osteoarthropathy.

[object Object] · Best Pract Res Clin Rheumatol · 2020

PMID: 32291203Review

Digital clubbing: forms, associations and pathophysiology.

[object Object], [object Object], [object Object] et al. · Br J Hosp Med (Lond) · 2016

PMID: 27388379Review

[Progress in genetic research on pachydermoperiostosis].

[object Object], [object Object], [object Object] et al. · Zhonghua Yi Xue Yi Chuan Xue Za Zhi · 2016

PMID: 26829746Review

Clubbing and hypertrophic osteoarthropathy: insights in diagnosis, pathophysiology, and clinical significance.

[object Object], [object Object], [object Object] et al. · Acta Clin Belg · 2016

PMID: 27104368Review

[Paraneoplastic syndromes and rheumatic diseases].

[object Object], [object Object], [object Object] · Postepy Hig Med Dosw (Online) · 2014

PMID: 25055033Review

Search all PubMed articles for Pachydermoperiostosis syndrome

Research data from MEDLINE/PubMed

Signs & Symptoms

Based on Human Phenotype Ontology (HPO) disease-phenotype annotations.

Abnormal compact bone morphology

Very frequent (80-99%)HP:0003103

Anomaly of the epiphyses

Very frequent (80-99%)HP:0005930

Bone infection

Very frequent (80-99%)HP:0002754

Bone pain

Very frequent (80-99%)HP:0002653

Diffusely thickened skin

Very frequent (80-99%)HP:0001072

Dysseborrheic dermatitis

Very frequent (80-99%)HP:0001051

Abnormal hair quantity

Frequent (30-79%)HP:0011362

Abnormality of the fingernails

Frequent (30-79%)HP:0001231

Acne

Frequent (30-79%)HP:0001061

Arthralgias

Frequent (30-79%)HP:0002829

Arthritis

Frequent (30-79%)HP:0001369

Breakdown of bone

Frequent (30-79%)HP:0002797

Clubbing of toes

Frequent (30-79%)HP:0100760

Eye drop

Frequent (30-79%)HP:0000508

Joint swelling

Frequent (30-79%)HP:0001386

Limitation of joint mobility

Frequent (30-79%)HP:0001376

Soft tissue swelling

Frequent (30-79%)HP:0000969

Thickened facial skin with coarse facial features

Frequent (30-79%)HP:0000280

Thickening of the scalp

Frequent (30-79%)HP:0010541

Abnormal distribution of hair

Occasional (5-29%)HP:0010720

Aseptic bone necrosis

Occasional (5-29%)HP:0010885

Bone marrow disease

Occasional (5-29%)HP:0005561

Occasional (5-29%)HP:0100021

Disproportionately small hands

Occasional (5-29%)HP:0200055

Elevated circulating growth hormone concentration

Occasional (5-29%)HP:0000845

Enlarged liver

Occasional (5-29%)HP:0002240

Gastrointestinal haemorrhage

Occasional (5-29%)HP:0002239

Genua vara

Occasional (5-29%)HP:0002970

Gynaecomastia

Occasional (5-29%)HP:0000771

Impaired thermal sensitivity

Occasional (5-29%)HP:0010829

Related Conditions

Hereditary disorder of musculoskeletal system(parent)

Periostitis(parent)

Hypertrophic condition of skin(parent)

Hereditary disorder of the integument(parent)

Recessive hereditary disorder (autosomal)(parent)

Hypertrophic osteoarthropathy(parent)

Genetic disorder of nail(parent)

Hippocratic nails(parent)

Quick Facts

SNOMED CT: 88220006
UMLS CUI: C0029411
Fully Specified Name: Pachydermoperiostosis syndrome (disorder)
Specialists: 0
Diagnostic Biomarkers: 0
HPO Phenotypes: 30

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Clinical content is derived from the SNOMED CT clinical ontology and curated medical knowledge graphs.