Signs & Symptoms
Based on Human Phenotype Ontology (HPO) disease-phenotype annotations.
High urine cortisol level
Very frequent (80-99%)HP:0012030
Hypercortisolism
Very frequent (80-99%)HP:0003118
Paradoxical increased cortisol secretion on dexamethasone suppression test
Very frequent (80-99%)HP:0003466
Pituitary corticotropic cell adenoma
Very frequent (80-99%)HP:0008291
Abdominal obesity
Frequent (30-79%)HP:0012743
Abnormality of the cardiovascular system
Frequent (30-79%)HP:0001626
Absolute lymphocyte count decrease
Frequent (30-79%)HP:0001888
Acne
Frequent (30-79%)HP:0001061
Amenorrhea
Frequent (30-79%)HP:0000141
Behavioral changes
Frequent (30-79%)HP:0000708
Bruising susceptibility
Frequent (30-79%)HP:0000978
Capillary fragility
Frequent (30-79%)HP:0025017
Decreased total eosinophil count
Frequent (30-79%)HP:0031891
Diabetes mellitus
Frequent (30-79%)HP:0000819
Dorsocervical fat pad
Frequent (30-79%)HP:0025383
Emotional lability
Frequent (30-79%)HP:0000712
Enlarged adrenal glands
Frequent (30-79%)HP:0008221
Fatiguable weakness of proximal limb muscles
Frequent (30-79%)HP:0030200
Gingival hyperpigmentation
Frequent (30-79%)HP:0010284
Glucose tolerance decreased
Frequent (30-79%)HP:0040270
High blood pressure
Frequent (30-79%)HP:0000822
Hirsutism
Frequent (30-79%)HP:0001007
Immune deficiency
Frequent (30-79%)HP:0002721
Increased body weight
Frequent (30-79%)HP:0004324
Increased circulating ACTH level
Frequent (30-79%)HP:0003154
Increased total leukocyte count
Frequent (30-79%)HP:0001974
Moon face
Frequent (30-79%)HP:0500011
Muscle weakness
Frequent (30-79%)HP:0001324
Osteoporosis
Frequent (30-79%)HP:0000939
Patchy darkened skin
Frequent (30-79%)HP:0000953
Quick Facts
- SNOMED CT
- 190502001
- UMLS CUI
- C0221406
- Fully Specified Name
- Pituitary-dependent Cushing's disease (disorder)
- Specialists
- 0
- Diagnostic Biomarkers
- 0
- HPO Phenotypes
- 30
Medical Disclaimer
This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.
Clinical content is derived from the SNOMED CT clinical ontology and curated medical knowledge graphs.