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Placental insufficiency

disorder
SNOMED 237292005CUI C0032051

Overview

Placental insufficiency is a disorder. There are currently 1 actively recruiting clinical trials.

Auto-generated from clinical reference data. Not a substitute for medical advice.

Research Evidence

Peer-reviewed studies linked via MeSH term "Placental Insufficiency" from the MEDLINE/PubMed database.

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Prediction of fetal and neonatal outcomes after preterm manifestations of placental insufficiency: systematic review of prediction models.
[object Object], [object Object], [object Object] et al. · Ultrasound Obstet Gynecol · 2023
PMID: 37161550Meta-Analysis
Should we offer prenatal exome sequencing for intrauterine growth restriction or short long bones? A systematic review and meta-analysis.
[object Object], [object Object], [object Object] et al. · Am J Obstet Gynecol · 2023
PMID: 36209938Meta-Analysis
The role of melatonin in pregnancies complicated by placental insufficiency: A systematic review.
[object Object], [object Object], [object Object] et al. · Eur J Obstet Gynecol Reprod Biol · 2022
PMID: 36108451Meta-Analysis
Heparin therapy in placental insufficiency: Systematic review and meta-analysis.
[object Object], [object Object], [object Object] et al. · Acta Obstet Gynecol Scand · 2020
PMID: 31519033Meta-Analysis
Effects of maternal smoking on human placental vascularization: A systematic review.
[object Object], [object Object], [object Object] et al. · Taiwan J Obstet Gynecol · 2019
PMID: 31307732Meta-Analysis
Early psychosocial development of small for gestational age and intrauterine growth-restricted children: a systematic review.
[object Object], [object Object], [object Object] et al. · J Perinatol · 2019
PMID: 30967654Meta-Analysis
Systematic review and meta-analysis of the test accuracy of ductus venosus Doppler to predict compromise of fetal/neonatal wellbeing in high risk pregnancies with placental insufficiency.
[object Object], [object Object], [object Object] et al. · Eur J Obstet Gynecol Reprod Biol · 2010
PMID: 20493624Meta-Analysis
Transcutaneous electrostimulation for suspected placental insufficiency (diagnosed by Doppler studies).
[object Object], [object Object] · Cochrane Database Syst Rev · 2000
PMID: 10796118Meta-AnalysisFull text (PMC)
Treatment of early-onset fetal growth restriction with low molecular weight heparin does not prolong gestation: a randomized clinical trial.
[object Object], [object Object], [object Object] et al. · Am J Obstet Gynecol · 2025
PMID: 39521297RCT

Signs & Symptoms

Based on Human Phenotype Ontology (HPO) disease-phenotype annotations.

Abnormality of the placenta
Always present (100%)HP:0100767
Abnormal umbilical cord blood vessel morphology
Very frequent (80-99%)HP:0011403
Birth weight less than 10th percentile
Very frequent (80-99%)HP:0001518
Hypoxia
Very frequent (80-99%)HP:0012418
Intrauterine growth retardation, IUGR
Very frequent (80-99%)HP:0001511
Short stature, proportionate
Very frequent (80-99%)HP:0003508
Small placenta
Very frequent (80-99%)HP:0006266
Antiphospholipid antibodies
Frequent (30-79%)HP:0003613
ASD
Frequent (30-79%)HP:0000729
Autism
Frequent (30-79%)HP:0000717
Neurodevelopmental abnormality
Frequent (30-79%)HP:0012759
SLE
Frequent (30-79%)HP:0002725
Abnormality of the lungs
Occasional (5-29%)HP:0002088
Body fails to respond to insulin
Occasional (5-29%)HP:0000855
Cardiac anomaly
Occasional (5-29%)HP:0001627
CP
Occasional (5-29%)HP:0100021

Quick Facts

SNOMED CT
237292005
UMLS CUI
C0032051
Fully Specified Name
Placental insufficiency (disorder)
Specialists
0
Diagnostic Biomarkers
0
HPO Phenotypes
16
Clinical Trials
3
Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Clinical content is derived from the SNOMED CT clinical ontology and curated medical knowledge graphs.