Overview
PLACK syndrome is a disorder.
Auto-generated from clinical reference data. Not a substitute for medical advice.
Signs & Symptoms
Based on Human Phenotype Ontology (HPO) disease-phenotype annotations.
Abnormal blistering of the skin
Always present (100%)HP:0008066
Acantholysis
Always present (100%)HP:0100792
Epidermal hyperkeratosis
Always present (100%)HP:0000962
Epidermal hyperplasia
Always present (100%)HP:0025092
Hyperkeratosis follicularis
Always present (100%)HP:0007502
Scaling skin
Always present (100%)HP:0040189
White discoloration of nails
Always present (100%)HP:0001820
Cheilitis
Frequent (30-79%)HP:0100825
Fragile skin
Frequent (30-79%)HP:0001030
Inflammation of oral commisures
Frequent (30-79%)HP:0030318
leukokeratosis
Frequent (30-79%)HP:0002745
Punctate palmoplantar hyperkeratosis
Frequent (30-79%)HP:0007530
Dorsal dupuytren nodules
Occasional (5-29%)HP:0032541
Dry skin
Occasional (5-29%)HP:0000958
Oncholysis
Occasional (5-29%)HP:0001806
Skin itching
Occasional (5-29%)HP:0000989
Telangiectasia on the cheeks
Occasional (5-29%)HP:0007421
Related Conditions
Leukonychia(parent)
Skin peeling disorder(parent)
Inherited disorder of keratinization(parent)
Punctate palmoplantar keratoderma(parent)
Genetic disorder of nail(parent)
Recessive hereditary disorder (autosomal)(parent)
Angular cheilitis(parent)
Digestive system hereditary disorder(parent)
Circumscribed palmoplantar keratoderma(parent)
Abnormality of skin appendage morphology(parent)
Quick Facts
- SNOMED CT
- 1237509001
- UMLS CUI
- C4225381
- Fully Specified Name
- Peeling skin, leukonychia, acral punctate keratoses, cheilitis, knuckle pads syndrome (disorder)
- Specialists
- 0
- Diagnostic Biomarkers
- 0
- HPO Phenotypes
- 17
Medical Disclaimer
This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.
Clinical content is derived from the SNOMED CT clinical ontology and curated medical knowledge graphs.