Primary sclerosing cholangitis

disorder

SNOMED 197441003CUI C0566602

Overview

Source: MedlinePlus.gov, National Library of Medicine. Not a substitute for medical advice.

Signs & Symptoms

Based on Human Phenotype Ontology (HPO) disease-phenotype annotations.

Anomaly of the biliary tract

Very frequent (80-99%)HP:0012440

Autoimmunity

Very frequent (80-99%)HP:0002960

Slowed or blocked flow of bile from liver

Very frequent (80-99%)HP:0001396

Abnormal large intestine physiology

Frequent (30-79%)HP:0012700

Ascites

Frequent (30-79%)HP:0001541

Cirrhosis

Frequent (30-79%)HP:0001394

Dilatation of the superficial abdominal veins

Frequent (30-79%)HP:0030168

Elevated alkaline phosphatase of hepatic origin

Frequent (30-79%)HP:0010638

Elevated liver enzymes

Frequent (30-79%)HP:0002910

Enlarged liver

Frequent (30-79%)HP:0002240

Hepatosplenomegaly

Frequent (30-79%)HP:0001433

Large spleen

Frequent (30-79%)HP:0001744

Liver fibrosis

Frequent (30-79%)HP:0001395

Portal hypertension

Frequent (30-79%)HP:0001409

Pyrexia

Frequent (30-79%)HP:0001945

Spider hemangioma

Frequent (30-79%)HP:0012522

Telangiectases of palms and soles

Frequent (30-79%)HP:0100869

Ulcerative colitis

Frequent (30-79%)HP:0100279

Weight loss

Frequent (30-79%)HP:0001824

Adenocarcinoma of the large intestine

Occasional (5-29%)HP:0040275

Cardiac insufficiency

Occasional (5-29%)HP:0001635

Cholangiocarcinoma

Occasional (5-29%)HP:0030153

Chronic hepatic failure

Occasional (5-29%)HP:0100626

Coeliac disease

Occasional (5-29%)HP:0002608

Deficient in vitamin D

Occasional (5-29%)HP:0100512

Depression

Occasional (5-29%)HP:0000716

Fluid around lungs

Occasional (5-29%)HP:0002202

Gallstones

Occasional (5-29%)HP:0001081

Hepatitis

Occasional (5-29%)HP:0012115

Increased incidence of hepatocellular carcinoma

Occasional (5-29%)HP:0001402

Related Conditions

Cirrhosis of liver with primary sclerosing cholangitis(child)

Sclerosing cholangitis(parent)

Quick Facts

SNOMED CT: 197441003
UMLS CUI: C0566602
Fully Specified Name: Primary sclerosing cholangitis (disorder)
Specialists: 0
Diagnostic Biomarkers: 0
HPO Phenotypes: 30

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Clinical content is derived from the SNOMED CT clinical ontology and curated medical knowledge graphs.