Overview
Punctate palmoplantar keratoderma type 1 is a disorder.
Auto-generated from clinical reference data. Not a substitute for medical advice.
Signs & Symptoms
Based on Human Phenotype Ontology (HPO) disease-phenotype annotations.
Punctate palmoplantar hyperkeratosis
Always present (100%)HP:0007530
Abnormality of epidermal morphology
Very frequent (80-99%)HP:0011124
Hyperkeratotic papule
Very frequent (80-99%)HP:0045059
Keratoderma
Very frequent (80-99%)HP:0000982
Palmoplantar keratosis
Very frequent (80-99%)HP:0000972
Epidermal hyperplasia
Frequent (30-79%)HP:0025092
Hypergranulosis
Frequent (30-79%)HP:0025114
Orthokeratosis
Frequent (30-79%)HP:0040162
Breast carcinoma
Occasional (5-29%)HP:0003002
Esophageal tumor
Occasional (5-29%)HP:0100751
Melanoma
Occasional (5-29%)HP:0002861
Pain
Occasional (5-29%)HP:0012531
Papillomatous papule
Occasional (5-29%)HP:0012500
Adenocarcinoma of the colon
Very rare (1-4%)HP:0040276
Adenocarcinoma of the small intestine
Very rare (1-4%)HP:0040274
Basal cell carcinoma
Very rare (1-4%)HP:0002671
Brain tumor
Very rare (1-4%)HP:0030692
Dystrophic nails
Very rare (1-4%)HP:0008404
Gastric cancer
Very rare (1-4%)HP:0012126
Hodgkin's lymphoma
Very rare (1-4%)HP:0012189
Lung tumor
Very rare (1-4%)HP:0100526
Neoplasm of the skeletal system
Very rare (1-4%)HP:0010622
Pancreatic adenocarcinoma
Very rare (1-4%)HP:0006725
Prostatic cancer
Very rare (1-4%)HP:0012125
Renal carcinoma
Very rare (1-4%)HP:0005584
Squamous cell carcinoma
Very rare (1-4%)HP:0002860
Abnormal hair morphology
Excluded (<1%)HP:0001595
Misshapened teeth
Excluded (<1%)HP:0006482
Nail disease
Excluded (<1%)HP:0001597
Quick Facts
- SNOMED CT
- 717184007
- UMLS CUI
- C1835662
- Fully Specified Name
- Punctate palmoplantar keratoderma type 1 (disorder)
- Specialists
- 0
- Diagnostic Biomarkers
- 0
- HPO Phenotypes
- 29
Medical Disclaimer
This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.
Clinical content is derived from the SNOMED CT clinical ontology and curated medical knowledge graphs.