Overview
Sézary's disease is a disorder.
Auto-generated from clinical reference data. Not a substitute for medical advice.
Treatments & Interventions
Research Evidence
Peer-reviewed studies linked via MeSH term "Syndrome, Sezary" from the MEDLINE/PubMed database.
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Allogeneic stem cell transplant for treatment of mycosis fungoides and Sezary syndrome: a systematic review and meta-analysis.
[object Object], [object Object], [object Object] · Bone Marrow Transplant · 2024
PMID: 37853164Meta-Analysis
Development of Cutaneous T-Cell Lymphoma Following Biologic Treatment: A Systematic Review.
[object Object], [object Object], [object Object] · Am J Clin Dermatol · 2023
PMID: 36627479Meta-Analysis
Diagnosis of mycosis fungoides or Sézary syndrome after dupilumab use: A systematic review.
[object Object], [object Object], [object Object] · J Am Acad Dermatol · 2023
PMID: 36481378Meta-Analysis
[Mycosis fungoides and Sézary syndrome : a systematic review].
[object Object], [object Object], [object Object] · Rev Med Suisse · 2022
PMID: 35353453Meta-Analysis
Mogamulizumab for Previously Treated Mycosis Fungoides and Sézary Syndrome: An Evidence Review Group Perspective of a NICE Single Technology Appraisal.
[object Object], [object Object], [object Object] et al. · Pharmacoeconomics · 2022
Quality of life in patients with Mycosis Fungoides and Sézary Syndrome: a systematic review of the literature.
[object Object], [object Object], [object Object] et al. · J Eur Acad Dermatol Venereol · 2021
Spectrum of mutational signatures in T-cell lymphoma reveals a key role for UV radiation in cutaneous T-cell lymphoma.
[object Object], [object Object], [object Object] et al. · Sci Rep · 2021
[Impact of algorithms proposed by the Cutaneous Lymphoma French Study Group for diagnosis of cutaneous lymphoproliferations].
[object Object], [object Object], [object Object] et al. · Ann Pathol · 2021
PMID: 33926757Meta-Analysis
Efficacy of Allogeneic Hematopoietic Cell Transplantation in Cutaneous T Cell Lymphoma: Results of a Systematic Review and Meta-Analysis.
[object Object], [object Object], [object Object] et al. · Biol Blood Marrow Transplant · 2020
PMID: 31494227Meta-Analysis
Insights into treatment of patients with mycosis fungoides or Sézary syndrome using mogamulizumab.
[object Object], [object Object], [object Object] et al. · J Dermatolog Treat · 2025
PMID: 39894454RCT
Search all PubMed articles for Sézary's disease
Research data from MEDLINE/PubMed
Signs & Symptoms
Based on Human Phenotype Ontology (HPO) disease-phenotype annotations.
Abnormal lymphocytes
Very frequent (80-99%)HP:0004332
Cancer of lymphatic system
Very frequent (80-99%)HP:0002665
Cellular immune defect
Very frequent (80-99%)HP:0002843
Cutaneous T-cell lymphoma
Very frequent (80-99%)HP:0012192
Dry skin
Very frequent (80-99%)HP:0000958
Erythroderma
Very frequent (80-99%)HP:0001019
Lichenification
Very frequent (80-99%)HP:0100725
Lymph node hyperplasia
Very frequent (80-99%)HP:0002716
Skin cancer (non-melanoma)
Very frequent (80-99%)HP:0008069
Skin itching
Very frequent (80-99%)HP:0000989
Dystrophic nails
Frequent (30-79%)HP:0008404
Enlarged liver
Frequent (30-79%)HP:0002240
Hair loss
Frequent (30-79%)HP:0001596
Immune deficiency
Frequent (30-79%)HP:0002721
Increased CD4:CD8 ratio
Frequent (30-79%)HP:0033221
Keratoderma
Frequent (30-79%)HP:0000982
Large spleen
Frequent (30-79%)HP:0001744
Abnormal immunoglobulin concentration
Occasional (5-29%)HP:0010701
Abnormal pleura morphology
Occasional (5-29%)HP:0002103
Chills
Occasional (5-29%)HP:0025143
Death of body tissue due to lack of blood flow or infection
Occasional (5-29%)HP:0100758
Edema
Occasional (5-29%)HP:0000969
Everted eyelid
Occasional (5-29%)HP:0000656
Hypothermia
Occasional (5-29%)HP:0002045
Irregular hyperpigmentation
Occasional (5-29%)HP:0007400
Neurogenic muscle atrophy, especially in the lower limbs
Occasional (5-29%)HP:0003202
Peripheral neuropathy
Occasional (5-29%)HP:0009830
Shuddering
Occasional (5-29%)HP:0025144
Tremor
Occasional (5-29%)HP:0001337
Related Conditions
Sezary's disease of lymph nodes of multiple sites(child)
Sézary's disease of spleen(child)
Sezary's disease of intrathoracic lymph nodes(child)
Sezary's disease of intra-abdominal lymph nodes(child)
Sezary's disease of lymph nodes of axilla and upper limb(child)
Sézary disease of lymph nodes of head and neck(child)
Sézary's disease of lymph nodes of inguinal region(child)
Primary cutaneous T-cell lymphoma(parent)
Mature T-cell AND/OR NK cell neoplasm(parent)
Quick Facts
- SNOMED CT
- 118611004
- UMLS CUI
- C0036920
- Fully Specified Name
- Sézary's disease (disorder)
- Specialists
- 0
- Diagnostic Biomarkers
- 0
- HPO Phenotypes
- 29
- Known Treatments
- 7
Medical Disclaimer
This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.
Clinical content is derived from the SNOMED CT clinical ontology and curated medical knowledge graphs.