Overview
Schilder's disease is a disorder.
Auto-generated from clinical reference data. Not a substitute for medical advice.
Research Evidence
Peer-reviewed studies linked via MeSH term "Diffuse Cerebral Sclerosis of Schilder" from the MEDLINE/PubMed database.
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Myelinoclastic diffuse sclerosis (Schilder's disease) is immunologically distinct from multiple sclerosis: results from retrospective analysis of 92 lumbar punctures.
[object Object], [object Object], [object Object] et al. · J Neuroinflammation · 2019
Balo concentric sclerosis, an emerging variant of multiple sclerosis: A case-series and literature review.
[object Object], [object Object], [object Object] et al. · J Neuroimmunol · 2025
PMID: 39842344Review
MRI signs of CNS demyelinating diseases.
[object Object], [object Object], [object Object] et al. · Mult Scler Relat Disord · 2021
PMID: 33310421Review
Baló's concentric sclerosis - A rare entity within the spectrum of demyelinating diseases.
[object Object], [object Object], [object Object] · J Neurol Sci · 2021
PMID: 34261000Review
Atypical inflammatory demyelinating lesions and atypical multiple sclerosis.
[object Object], [object Object], [object Object] · Rev Neurol (Paris) · 2018
PMID: 29673573Review
Balo's concentric sclerosis: an update and comprehensive literature review.
[object Object], [object Object], [object Object] et al. · Rev Neurosci · 2018
PMID: 29768251Review
[Mitochondrial diseases and epilepsy].
[object Object] · Zhongguo Dang Dai Er Ke Za Zhi · 2017
Exploring the overlap between multiple sclerosis, tumefactive demyelination and Baló's concentric sclerosis.
[object Object], [object Object], [object Object] · Mult Scler · 2016
PMID: 27037180Review
Myoclonus epilepsy in mitochondrial disorders.
[object Object], [object Object] · Epileptic Disord · 2016
PMID: 27618766Review
"Clues on Balo's concentric sclerosis evolution from serial analysis of ADC values".
[object Object], [object Object], [object Object] et al. · Int J Neurosci · 2016
PMID: 25405537Review
Search all PubMed articles for Schilder's disease
Research data from MEDLINE/PubMed
Signs & Symptoms
Based on Human Phenotype Ontology (HPO) disease-phenotype annotations.
Demyelination in central white matter
Frequent (30-79%)HP:0007305
Elevated csf protein
Frequent (30-79%)HP:0002922
Headache
Frequent (30-79%)HP:0002315
Hyperintensity of cerebral white matter on MRI
Frequent (30-79%)HP:0030890
Increased reflexes
Frequent (30-79%)HP:0001347
Worsening neurological symptoms
Frequent (30-79%)HP:0002344
Abnormal retropulsion test
Occasional (5-29%)HP:0002172
Ankle clonus
Occasional (5-29%)HP:0011448
Ataxia
Occasional (5-29%)HP:0001251
Cerebrospinal fluid pleocytosis
Occasional (5-29%)HP:0012229
Double vision
Occasional (5-29%)HP:0000651
Encephalopathy
Occasional (5-29%)HP:0001298
Esotropia
Occasional (5-29%)HP:0000565
Muscle weakness
Occasional (5-29%)HP:0001324
Nausea
Occasional (5-29%)HP:0002018
Pseudotumor cerebri
Occasional (5-29%)HP:0002516
Seizures
Occasional (5-29%)HP:0001250
Vertigo
Occasional (5-29%)HP:0002321
Vomiting
Occasional (5-29%)HP:0002013
CVI
HP:0100704
Diffuse cerebral sclerosis
HP:0006918
Related Conditions
Quick Facts
- SNOMED CT
- 49692006
- UMLS CUI
- C0007795
- Fully Specified Name
- Schilder's disease (disorder)
- Specialists
- 0
- Diagnostic Biomarkers
- 0
- HPO Phenotypes
- 21
Medical Disclaimer
This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.
Clinical content is derived from the SNOMED CT clinical ontology and curated medical knowledge graphs.