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Schnitzler syndrome

disorder
SNOMED 402415001CUI C0524988

Overview

Source: MedlinePlus.gov, National Library of Medicine. Not a substitute for medical advice.

Research Evidence

Peer-reviewed studies linked via MeSH term "Schnitzler Syndrome" from the MEDLINE/PubMed database.

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Schnitzler syndrome without monoclonal gammopathy: a  systematic review and case presentation.
[object Object], [object Object], [object Object] et al. · Clin Exp Dermatol · 2025
PMID: 40971739Meta-Analysis
Efficacy and safety of canakinumab treatment in schnitzler syndrome: A systematic literature review.
[object Object], [object Object], [object Object] · Semin Arthritis Rheum · 2020
PMID: 32502728Meta-Analysis
Schnitzler's syndrome: diagnosis, treatment, and follow-up.
[object Object], [object Object], [object Object] et al. · Allergy · 2013
PMID: 23480774Meta-Analysis
Chronic urticaria and autoinflammatory syndromes.
[object Object], [object Object], [object Object] · Curr Opin Allergy Clin Immunol · 2025
PMID: 40747632Review
Schnitzler syndrome.
[object Object], [object Object] · Dermatologie (Heidelb) · 2025
PMID: 31165908Review
Acquired autoinflammatory disorders: a dermatologist's perspective.
[object Object], [object Object], [object Object] et al. · Clin Exp Dermatol · 2025
PMID: 39671562Review
Neutrophilic Urticarial Dermatosis.
[object Object], [object Object], [object Object] et al. · Dermatol Clin · 2024
PMID: 38423683Review
Inflammatory turmoil within: an exploration of autoinflammatory disease genetic underpinnings, clinical presentations, and therapeutic approaches.
[object Object], [object Object], [object Object] et al. · Adv Rheumatol · 2024
PMID: 39175060Review

Signs & Symptoms

Based on Human Phenotype Ontology (HPO) disease-phenotype annotations.

Arthralgias
Very frequent (80-99%)HP:0002829
Arthritis
Very frequent (80-99%)HP:0001369
Bone pain
Very frequent (80-99%)HP:0002653
Enlarged liver
Very frequent (80-99%)HP:0002240
Flat, discolored area of skin
Very frequent (80-99%)HP:0012733
Hives
Very frequent (80-99%)HP:0001025
Increased bone mineral density
Very frequent (80-99%)HP:0011001
Increased IgM levels
Very frequent (80-99%)HP:0003496
Large spleen
Very frequent (80-99%)HP:0001744
Muscle pain
Very frequent (80-99%)HP:0003326
Papules
Very frequent (80-99%)HP:0200034
Pyrexia
Very frequent (80-99%)HP:0001945
Skin rash
Very frequent (80-99%)HP:0000988
Decreased haemoglobin
Frequent (30-79%)HP:0001903
Increased total leukocyte count
Frequent (30-79%)HP:0001974
Tiredness
Frequent (30-79%)HP:0012378
Cancer of lymphatic system
Occasional (5-29%)HP:0002665
Inflammation of blood vessel
Occasional (5-29%)HP:0002633
Lymph node hyperplasia
Occasional (5-29%)HP:0002716
Peripheral neuropathy
Occasional (5-29%)HP:0009830
Skin itching
Occasional (5-29%)HP:0000989

Quick Facts

SNOMED CT
402415001
UMLS CUI
C0524988
Fully Specified Name
Schnitzler syndrome (disorder)
Specialists
0
Diagnostic Biomarkers
0
HPO Phenotypes
21
Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Clinical content is derived from the SNOMED CT clinical ontology and curated medical knowledge graphs.