Overview
Spinocerebellar ataxia type 25 is a disorder.
Auto-generated from clinical reference data. Not a substitute for medical advice.
Signs & Symptoms
Based on Human Phenotype Ontology (HPO) disease-phenotype annotations.
Ataxia
Always present (100%)HP:0001251
Decreased number of large and small myelinated fibres
Always present (100%)HP:0003380
Abolished vibration sense
Very frequent (80-99%)HP:0006944
Infratentorial atrophy
Very frequent (80-99%)HP:0001272
Progressive cerebellar ataxia
Very frequent (80-99%)HP:0002073
Abnormal cerebellar cortex morphology
Frequent (30-79%)HP:0031422
Areflexia in lower limbs
Frequent (30-79%)HP:0002522
Cobb angle greater than ten degrees
Frequent (30-79%)HP:0002650
Diffuse cerebellar atrophy
Frequent (30-79%)HP:0100275
EMG: neuropathic changes
Frequent (30-79%)HP:0003445
Extensor plantar responses
Frequent (30-79%)HP:0003487
Hypoacusis
Frequent (30-79%)HP:0000365
Impaired distal tactile sensation
Frequent (30-79%)HP:0006937
Impaired pain sensation
Frequent (30-79%)HP:0007328
Inability to coordinate movements when walking
Frequent (30-79%)HP:0002066
Involuntary facial muscle spasms
Frequent (30-79%)HP:0011468
Involuntary, rapid, rhythmic eye movements
Frequent (30-79%)HP:0000639
Loss of distal sensation
Frequent (30-79%)HP:0002936
Loss of large myelinated fibres
Frequent (30-79%)HP:0003387
Overactive bladder syndrome
Frequent (30-79%)HP:0000012
Pes cavus
Frequent (30-79%)HP:0001761
Rigid dysarthria
Frequent (30-79%)HP:0002464
Sensory neuropathy
Frequent (30-79%)HP:0000763
Squint
Frequent (30-79%)HP:0000486
Cortical white matter abnormalities seen on MRI
Occasional (5-29%)HP:0002500
Defective or absent horizontal voluntary eye movements
Occasional (5-29%)HP:0000657
Intermittent abdominal pain
Occasional (5-29%)HP:0002574
Involuntary facial quivering
Occasional (5-29%)HP:0000317
Vomiting
Occasional (5-29%)HP:0002013
Decreased visual acuity
HP:0007663
Quick Facts
- SNOMED CT
- 718770005
- UMLS CUI
- C1837518
- Fully Specified Name
- Spinocerebellar ataxia type 25 (disorder)
- Specialists
- 0
- Diagnostic Biomarkers
- 0
- HPO Phenotypes
- 30
Medical Disclaimer
This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.
Clinical content is derived from the SNOMED CT clinical ontology and curated medical knowledge graphs.