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Undifferentiated connective tissue disease

disorder
SNOMED 239918008CUI C0409999

Overview

Source: MedlinePlus.gov, National Library of Medicine. Not a substitute for medical advice.

Research Evidence

Peer-reviewed studies linked via MeSH term "Undifferentiated Connective Tissue Diseases" from the MEDLINE/PubMed database.

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Undifferentiated Connective Tissue Disease: Comprehensive Review.
[object Object], [object Object] · Curr Rheumatol Rep · 2023
PMID: 36884206Meta-Analysis
Predicting progression from undifferentiated connective tissue disease to definite connective tissue disease: A systematic review and meta-analysis.
[object Object], [object Object], [object Object] et al. · Autoimmun Rev · 2022
PMID: 36031048Meta-Analysis
Comparing pregnancy outcomes in patients with criteria and non-criteria autoimmune disease: A systematic review.
[object Object], [object Object], [object Object] et al. · Lupus · 2022
PMID: 34866492Meta-Analysis
[Rethinking diagnosis and differential diagnosis in rheumatic and immunologic diseases from the perspective of undifferentiated diseases].
[object Object], [object Object], [object Object] · Zhonghua Er Ke Za Zhi · 2025
PMID: 41233121Review
Differentiating between UCTD and early-stage SLE: from definitions to clinical approach.
[object Object], [object Object], [object Object] et al. · Nat Rev Rheumatol · 2022
PMID: 34764455Review
Interstitial Pneumonia with Autoimmune Features and Undifferentiated Connective Tissue Disease.
[object Object], [object Object], [object Object] · Semin Respir Crit Care Med · 2019
PMID: 31137065Review

Signs & Symptoms

Based on Human Phenotype Ontology (HPO) disease-phenotype annotations.

Anti-dsDNA antibody positivity
Frequent (30-79%)HP:0020151
Anti-ribosome Po antibody positivity
Frequent (30-79%)HP:0034076
Anti-Ro52/TRIM21 antibody positivity
Frequent (30-79%)HP:0034093

Quick Facts

SNOMED CT
239918008
UMLS CUI
C0409999
Fully Specified Name
Undifferentiated connective tissue disease (disorder)
Specialists
0
Diagnostic Biomarkers
0
HPO Phenotypes
3
Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Clinical content is derived from the SNOMED CT clinical ontology and curated medical knowledge graphs.