Substance / Medication

Acamprosate

Overview

Active Ingredient
acamprosate
RxNorm CUI
82819

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Administration details including route, dosing schedules, preparation instructions, and contraindications are pending physician authorship.

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Clinical Trials

116 trials linked to this intervention

116
Total Trials
19
Recruiting
46
With Results

Research Evidence

Published studies and systematic reviews

Sort:
The rates and measurement of adherence to acamprosate in randomised controlled clinical trials: A systematic review.
Donoghue Kim, Hermann Laura, Brobbin Eileen et al. · PLoS One · 2022
PMID: 35113930Meta-AnalysisFull text (PMC)
The efficacy of acamprosate and naltrexone in the treatment of alcohol dependence, Europe versus the rest of the world: a meta-analysis.
Donoghue Kim, Elzerbi Catherine, Saunders Rob et al. · Addiction · 2015
PMID: 25664494Meta-Analysis
The placebo effect in clinical trials for alcohol dependence: an exploratory analysis of 51 naltrexone and acamprosate studies.
Litten Raye Z, Castle I-Jen P, Falk Daniel et al. · Alcohol Clin Exp Res · 2013
PMID: 23889231Meta-AnalysisFull text (PMC)
Acamprosate for alcohol dependence: a sex-specific meta-analysis based on individual patient data.
Mason Barbara J, Lehert Philippe · Alcohol Clin Exp Res · 2012
PMID: 21895717Meta-AnalysisFull text (PMC)
[Meta-analysis of pharmacological therapy with acamprosate, naltrexone, and disulfiram--a systematic review].
Petrov Igor, Krogh Jesper, Nordentoft Merete · Ugeskr Laeger · 2011
PMID: 22118653Meta-Analysis
Acamprosate for alcohol dependence.
Rösner Susanne, Hackl-Herrwerth Andrea, Leucht Stefan et al. · Cochrane Database Syst Rev · 2010
PMID: 20824837Meta-AnalysisFull text (PMC)
Effect of early and late compliance on the effectiveness of acamprosate in the treatment of alcohol dependence.
Koeter Maarten W J, van den Brink Wim, Lehert Philippe · J Subst Abuse Treat · 2010
PMID: 20627222Meta-Analysis
Acamprosate supports abstinence, naltrexone prevents excessive drinking: evidence from a meta-analysis with unreported outcomes.
Rösner Susanne, Leucht Stefan, Lehert Philippe et al. · J Psychopharmacol · 2008
PMID: 18187529Meta-Analysis

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type
Substance / Medication
Fully Specified Name
Acamprosate (substance)
SNOMED CT
391698009
UMLS CUI
C0284941
RxNorm CUI
82819

Clinical Data

This intervention maps to 3 entities in the Ltrl knowledge graph.

3
Conditions
0
Biomarkers
0
Specialists
0
Symptoms
116
Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Ltrl clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.