Substance / Medication

Anakinra

Overview

Active Ingredient
anakinra
RxNorm CUI
72435
Labeler: Swedish Orphan Biovitrum AB (publ)Updated: 2025-11-05T00:00:00.000ZFull label on DailyMed

Contraindications

When this intervention should not be used

E coli 5.3 [see Hypersensitivity Reactions ()] KINERET is contraindicated in patients with known hypersensitivity to-derived proteins, KINERET, or any components of the product.

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Detailed dosage and administration information is available in the full FDA drug label.

View full prescribing information on DailyMed

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

Research Evidence

Published studies and systematic reviews

Sort:
Effectiveness of early Anakinra on cardiac function in children with multisystem inflammatory syndrome of COVID-19: a systematic review.
Shabil Muhammed, Khatib Mahalaqua Nazli, Banda Godfrey T et al. · BMC Infect Dis · 2024
PMID: 39169304Meta-AnalysisFull text (PMC)
A meta analysis on the utility of Anakinra in severe COVID-19 disease.
Mohamed Hussein Aliae A R, Sayad Reem, Abdelshafi Abdelrahman et al. · Cytokine · 2023
PMID: 37536222Meta-Analysis
Anakinra for the Treatment of Antisynthetase Syndrome: A Monocentric Case Series and a Systematic Literature Review.
Campochiaro Corrado, Farina Nicola, De Luca Giacomo et al. · J Rheumatol · 2023
PMID: 36109081Meta-Analysis
Anakinra for the treatment of COVID-19 patients: a systematic review and meta-analysis.
Dahms Karolina, Mikolajewska Agata, Ansems Kelly et al. · Eur J Med Res · 2023
PMID: 36841793Meta-AnalysisFull text (PMC)
Intravenous anakinra for the treatment of haemophagocytic lymphohistiocytosis/macrophage activation syndrome: A systematic review.
Charlesworth James E G, Kavirayani Akhila · Eur J Haematol · 2023
PMID: 37344166Meta-Analysis
The efficacy of anakinra compared to standard care of treatment for COVID-19: a meta-analysis.
Malık Hamna, Bınt Abdul Jabbar Hira, Latıf Farah et al. · Turk J Med Sci · 2022
PMID: 36326309Meta-AnalysisFull text (PMC)
Anakinra in Heart Failure: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
Mahfooz Kamran, Rana Aditya, Palagati Keerthi et al. · Med Sci (Basel) · 2022
PMID: 36649041Meta-AnalysisFull text (PMC)
Anakinra treatment efficacy in reduction of inflammatory biomarkers in COVID-19 patients: A meta-analysis.
Naveed Zunaira, Sarwar Musharraf, Ali Zahid et al. · J Clin Lab Anal · 2022
PMID: 35435272Meta-AnalysisFull text (PMC)

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Adverse reaction and safety data for this drug is sourced from the FDA-approved label.

View adverse reactions & drug interactions on DailyMed

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Specialists

Providers who commonly manage this intervention

Health Goals

Goals connected through associated conditions

Quick Facts

Type
Substance / Medication
Fully Specified Name
Anakinra (substance)
SNOMED CT
385549000
UMLS CUI
C0245109
RxNorm CUI
72435
Labeler
Swedish Orphan Biovitrum AB (publ)

Clinical Data

This intervention maps to 7 entities in the Ltrl knowledge graph.

2
Conditions
2
Biomarkers
1
Specialists
0
Symptoms

Data is sourced from SNOMED CT, UMLS, and the Ltrl clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.