Substance / Medication

Atezolizumab

Overview

Active Ingredient
atezolizumab
RxNorm CUI
1792776
Labeler: Genentech, Inc.Updated: 2025-12-03T00:00:00.000ZFull label on DailyMed

Contraindications

When this intervention should not be used

TECENTRIQ HYBREZA is contraindicated in patients with known hypersensitivity to hyaluronidase or to any of its excipients.

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Detailed dosage and administration information is available in the full FDA drug label.

View full prescribing information on DailyMed

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Clinical Trials

6 trials linked to this intervention

6
Total Trials
4
Recruiting
1
With Results

Research Evidence

Published studies and systematic reviews

Sort:
Efficacy and safety of atezolizumab in the treatment of urothelial carcinoma: a systematic review and meta-analysis.
Xie Jun, Mao Qiu-Yu, Chen Jun-Hao et al. · World J Surg Oncol · 2025
PMID: 40205427Meta-AnalysisFull text (PMC)
Efficacy and Safety of Lenvatinib versus Atezolizumab Plus Bevacizumab in the Treatment of Unresectable Hepatocellular Carcinoma: A Systematic Review and Meta-Analysis.
Remitha Ni Putu Sri Indrani, Dewi Ni Putu Rista Pradnya, Kusuma I Komang Wira Ananta et al. · Asian Pac J Cancer Prev · 2025
PMID: 40439364Meta-AnalysisFull text (PMC)
Atezolizumab Plus Bevacizumab Versus Lenvatinib for Hepatocellular Carcinoma: A Systematic Review and Meta-Analysis.
Lu Jinpeng, Lin Xinyi, Teng Haiwen et al. · J Clin Pharmacol · 2024
PMID: 38311835Meta-Analysis
Efficacy of Atezolizumab Plus Bevacizumab Versus Lenvatinib in Patients with Unresectable Hepatocellular Carcinoma: a Meta-analysis.
Changez Mah I Kan, Khan Maimoona, Uzair Muhammad et al. · J Gastrointest Cancer · 2024
PMID: 38095799Meta-Analysis
Atezolizumab and Bevacizumab Targeted-Therapy in Advanced Hepatocellular Carcinoma: A Systematic Review of Cost-effectiveness Analyses.
Mohammadnezhad Ghader, Esmaily Hadi, Talebi Maryam et al. · J Gastrointest Cancer · 2024
PMID: 38488933Meta-Analysis
Atezolizumab as the First Systemic Therapy Approved for Alveolar Soft Part Sarcoma.
Bergsma Emilie J, Elgawly Mariam, Mancuso David et al. · Ann Pharmacother · 2024
PMID: 37466080Review

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Adverse reaction and safety data for this drug is sourced from the FDA-approved label.

View adverse reactions & drug interactions on DailyMed

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type
Substance / Medication
Fully Specified Name
Atezolizumab (substance)
SNOMED CT
719371003
UMLS CUI
C4055433
RxNorm CUI
1792776
Labeler
Genentech, Inc.

Clinical Data

This intervention maps to 8 entities in the Ltrl knowledge graph.

8
Conditions
0
Biomarkers
0
Specialists
0
Symptoms
6
Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Ltrl clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.