Substance / Medication

Bazedoxifene

Overview

Active Ingredient
bazedoxifene
RxNorm CUI
1441386

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

No related conditions have been mapped yet. Condition-intervention linkages are derived from SNOMED CT relationships and will expand as the knowledge graph grows.

Administration & Protocol

Dosing, route, and treatment protocol

Administration details including route, dosing schedules, preparation instructions, and contraindications are pending physician authorship.

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Clinical Trials

4 trials linked to this intervention

4
Total Trials
0
Recruiting
2
With Results

Research Evidence

Published studies and systematic reviews

Sort:
Bazedoxifene plus conjugated estrogens improve menopausal symptoms in postmenopausal women: a systematic review and meta-analysis.
Bi Beilei, Jiang Yi, Shi Yin et al. · Gynecol Endocrinol · 2022
PMID: 36036169Meta-Analysis
Cardiovascular safety of conjugated estrogens plus bazedoxifene: meta-analysis of the SMART trials.
Komm B S, Thompson J R, Mirkin S · Climacteric · 2015
PMID: 25511453Meta-Analysis
Bazedoxifene plus conjugated estrogen to treat menopausal depression-A pilot study.
Kulkarni Jayashri, Mu Eveline, Li Qi et al. · J Pharmacol Exp Ther · 2025
PMID: 40139074RCT
Effectiveness of bazedoxifene in preventing glucocorticoid-induced bone loss in rheumatoid arthritis patients.
Cho Soo-Kyung, Kim Hyoungyoung, Lee Jiyoung et al. · Arthritis Res Ther · 2021
PMID: 34215316RCTFull text (PMC)
Effect of conjugated estrogens and bazedoxifene on glucose, energy and lipid metabolism in obese postmenopausal women.
Marlatt Kara L, Lovre Dragana, Beyl Robbie A et al. · Eur J Endocrinol · 2020
PMID: 32698159RCTFull text (PMC)
Time to transient and stable reductions in hot flush frequency in postmenopausal women using conjugated estrogens/bazedoxifene.
Pinkerton JoAnn V, Bushmakin Andrew G, Abraham Lucy et al. · Menopause · 2017
PMID: 28463874RCT

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type
Substance / Medication
Fully Specified Name
Bazedoxifene (substance)
SNOMED CT
440186005
UMLS CUI
C2346970
RxNorm CUI
1441386

Clinical Data

This intervention maps to 0 entities in the Ltrl knowledge graph.

0
Conditions
0
Biomarkers
0
Specialists
0
Symptoms
4
Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Ltrl clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.