Substance / Medication

Benzoyl peroxide

Overview

Active Ingredient
benzoyl peroxide
RxNorm CUI
1418

Indications

Adapalene and benzoyl peroxide gel is indicated for the topical treatment of acne vulgaris in patients 9 years of age and older.

Labeler: Glenmark Pharmaceuticals Inc., USAUpdated: 2026-11-23T00:00:00.000ZFull label on DailyMed

Contraindications

When this intervention should not be used

None

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Detailed dosage and administration information is available in the full FDA drug label.

View full prescribing information on DailyMed

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Clinical Trials

123 trials linked to this intervention

123
Total Trials
6
Recruiting
78
With Results

Research Evidence

Published studies and systematic reviews

Sort:
Tretinoin 0.1% and Benzoyl Peroxide 3% Cream for the Treatment of Facial Acne Vulgaris.
Kontzias Christina, Zaino Mallory, Feldman Steven R · Ann Pharmacother · 2023
PMID: 36639853Meta-Analysis
Preoperative topical benzoyl peroxide treatment is effective in reducing Cutibacterium acnes in shoulder surgery: a systematic review.
Green Natalie, Jordan Robert W, Maclean Simon et al. · J Shoulder Elbow Surg · 2023
PMID: 36067940Meta-Analysis
Topical benzoyl peroxide for acne.
Yang Zhirong, Zhang Yuan, Lazic Mosler Elvira et al. · Cochrane Database Syst Rev · 2020
PMID: 32175593Meta-AnalysisFull text (PMC)
A subgroup analysis to evaluate the efficacy and safety of adapalene-benzoyl peroxide topical gel in black subjects with moderate acne.
Alexis Andrew F, Johnson Lori A, Kerrouche Nabil et al. · J Drugs Dermatol · 2014
PMID: 24509968Meta-Analysis
A systematic review of benzoyl peroxide for acne vulgaris.
Mohd Nor Noor Hidayah, Aziz Zoriah · J Dermatolog Treat · 2013
PMID: 22658322Meta-Analysis
The efficacy of adapalene-benzoyl peroxide combination increases with number of acne lesions.
Feldman Steven R, Tan Jerry, Poulin Yves et al. · J Am Acad Dermatol · 2011
PMID: 21439678Meta-Analysis

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Adverse reaction and safety data for this drug is sourced from the FDA-approved label.

View adverse reactions & drug interactions on DailyMed

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type
Substance / Medication
Fully Specified Name
Benzoyl peroxide (substance)
SNOMED CT
91598004
UMLS CUI
C0005088
RxNorm CUI
1418
Labeler
Glenmark Pharmaceuticals Inc., USA

Clinical Data

This intervention maps to 2 entities in the Ltrl knowledge graph.

2
Conditions
0
Biomarkers
0
Specialists
0
Symptoms
123
Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Ltrl clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.