Substance / Medication

Bosentan monohydrate

Overview

Active Ingredient
bosentan monohydrate
RxNorm CUI
498193

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Administration details including route, dosing schedules, preparation instructions, and contraindications are pending physician authorship.

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Clinical Trials

55 trials linked to this intervention

55
Total Trials
13
Recruiting
16
With Results

Research Evidence

Published studies and systematic reviews

Sort:
The volume-outcome relationship for pulmonary endarterectomy in chronic thromboembolic pulmonary hypertension.
Heuts Samuel, Kawczynski Michal J, Leus Arthur et al. · Eur Respir J · 2025
PMID: 39572220Meta-AnalysisFull text (PMC)
Pulmonary hypertension in preterm neonates with bronchopulmonary dysplasia: a meta-analysis.
Mascarenhas Dwayne, Al-Balushi Marwa, Al-Sabahi Aida et al. · Arch Dis Child Fetal Neonatal Ed · 2025
PMID: 39603794Meta-Analysis
Efficacy of iron replacement in pulmonary hypertension: A systematic review.
Baral Tejaswini, Malakapogu Pravachana, Shyma Zuha et al. · Nutr Health · 2025
PMID: 39711168Meta-AnalysisFull text (PMC)
Efficacy and Safety of Treating Pulmonary Arterial Hypertension With Imatinib: A Meta-Analysis of Randomized Controlled Trials.
Chen Xiaofa, Xue Bijuan, Xu Lina · J Cardiovasc Pharmacol · 2025
PMID: 39745285Meta-Analysis
Insights from 3D echocardiography: unveiling the prognostic value of RV function in pulmonary hypertension: a systematic review and meta-analysis.
Ahmad Ashfaq, Wang Xiaoyu, Li Lingling et al. · Int J Cardiovasc Imaging · 2025
PMID: 39806166Meta-Analysis
Bosentan monohydrate and sildenafil base as two companions in enabling formulations.
Strojewski Dominik, Lalik Sebastian, Danède Florence et al. · Int J Pharm · 2024
PMID: 38876441Other
Preparation and characterization of bosentan monohydrate/ε-polycaprolactone nanoparticles obtained by electrospraying.
Giménez Virna M, Sperandeo Norma, Faudone Sonia et al. · Biotechnol Prog · 2019
PMID: 30548149Other
Development and Validation of a UHPLC UV Method for the In-Process Control of Bosentan Monohydrate Synthesis.
Jatczak Marta, Sidoryk Katarzyna, Kossykowska Magdalena et al. · Chromatographia · 2016
PMID: 27616782OtherFull text (PMC)
Bosentan monohydrate.
Kaur Manpreet, Jasinski Jerry P, Keeley Amanda C et al. · Acta Crystallogr Sect E Struct Rep Online · 2013
PMID: 23476382OtherFull text (PMC)

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type
Substance / Medication
Fully Specified Name
Bosentan monohydrate (substance)
SNOMED CT
725734005
UMLS CUI
C1529800
RxNorm CUI
498193

Clinical Data

This intervention maps to 1 entities in the Ltrl knowledge graph.

1
Conditions
0
Biomarkers
0
Specialists
0
Symptoms
55
Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Ltrl clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.