Substance / Medication

Buspirone hydrochloride

Overview

Clinical overview including description, indications, and evidence base is pending physician authorship or FDA SPL integration. Graph-derived relationship data is available below.

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Administration details including route, dosing schedules, preparation instructions, and contraindications are pending physician authorship.

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

Clinical Trials

48 trials linked to this intervention

48
Total Trials
5
Recruiting
17
With Results

Research Evidence

Published studies and systematic reviews

Sort:
Enhanced bioavailability of buspirone hydrochloride via cup and core buccal tablets: formulation and in vitro/in vivo evaluation.
Kassem Mohamed A A, Elmeshad Aliaa N, Fares Ahmed R · Int J Pharm · 2014
PMID: 24412520RCT
Controlled release effervescent buccal discs of buspirone hydrochloride: in vitro and in vivo evaluation studies.
Jaipal A, Pandey M M, Charde S Y et al. · Drug Deliv · 2016
PMID: 24892624Observational
Brain targeting studies on buspirone hydrochloride after intranasal administration of mucoadhesive formulation in rats.
Khan Shagufta, Patil Kundan, Yeole Pramod et al. · J Pharm Pharmacol · 2009
PMID: 19406007Observational
Enhanced iontophoretic delivery of buspirone hydrochloride across human skin using chemical enhancers.
Meidan Victor M, Al-Khalili Mohammad, Michniak Bozena B · Int J Pharm · 2003
PMID: 12972337Observational
A bedside-savior for insomnia and anxiety disorders: melatonin/buspirone hydrochloride compound oral fast-dissolving film.
Liu Xiaoyan, Chu Chenxiao, Lu Qianru et al. · Eur J Pharm Biopharm · 2026
PMID: 41218725Other
Buspirone hydrochloride: a potential regulator of PD-L1 for enhanced antitumor activity in melanoma-bearing mice.
Geng Jiaxin, Wang Kangle, Zhang Sheping et al. · J Drug Target · 2026
PMID: 41489440Other
Development of buspirone hydrochloride-loaded long-acting microneedles for management of anxiety disorders.
Karve Tanvi, Shrestha Nisha, Kipping Thomas et al. · Drug Deliv Transl Res · 2025
PMID: 39953340OtherFull text (PMC)
Buspirone Hydrochloride Polymorphism: Stability, Solubility, Flow Properties, and Manufacturing Implications.
Janning Jéssika Adriane, Santiago Victória Guimarães, Ferreira Ederlan de Souza et al. · Adv Pharmacol Pharm Sci · 2025
PMID: 41113553OtherFull text (PMC)
Preparation, Swelling, and Drug Release Studies of Chitosan-based Hydrogels for Controlled Delivery of Buspirone Hydrochloride.
Suhail Muhammad, Fang Chih-Wun, Chiu I-Hui et al. · Curr Pharm Biotechnol · 2024
PMID: 38204236Other

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Health Goals

Goals connected through associated conditions

Quick Facts

Type
Substance / Medication
Fully Specified Name
Buspirone hydrochloride (substance)
SNOMED CT
419484002
UMLS CUI
C0700444

Clinical Data

This intervention maps to 11 entities in the Ltrl knowledge graph.

3
Conditions
4
Biomarkers
2
Specialists
0
Symptoms
48
Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Ltrl clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.