Substance / Medication

Cefuroxime

Overview

Active Ingredient
cefuroxime
RxNorm CUI
2194

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Administration details including route, dosing schedules, preparation instructions, and contraindications are pending physician authorship.

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Clinical Trials

133 trials linked to this intervention

133
Total Trials
32
Recruiting
17
With Results

Research Evidence

Published studies and systematic reviews

Sort:
Efficacy of perioperative cefuroxime as a prophylactic antibiotic in women requiring caesarean section: A systematic review.
Alrammaal Hanadi H, Batchelor Hannah K, Morris R Katie et al. · Eur J Obstet Gynecol Reprod Biol · 2019
PMID: 31569027Meta-Analysis
Comparative analysis of the safety and efficacy of intracameral cefuroxime, moxifloxacin and vancomycin at the end of cataract surgery: a meta-analysis.
Bowen Randy C, Zhou Andrew Xingyu, Bondalapati Sailaja et al. · Br J Ophthalmol · 2018
PMID: 29326317Meta-AnalysisFull text (PMC)
Impact of Early Exposure to Cefuroxime on the Composition of the Gut Microbiota in Infants Following Cesarean Delivery.
Kamal Shamrulazhar S, Hyldig Nana, Krych Łukasz et al. · J Pediatr · 2019
PMID: 31053348RCT
Pharmacokinetics of cefuroxime after intravenous, intramuscular, and subcutaneous administration to dogs.
Albarellos G A, Montoya L, Lorenzini P M et al. · J Vet Pharmacol Ther · 2016
PMID: 25982523RCT
The half-life and exposure of cefuroxime varied in newborn infants after a Caesarean section.
Zachariassen G, Hyldig N, Joergensen J S et al. · Acta Paediatr · 2016
PMID: 27240549RCT
Effects of amlodipine on the oral bioavailability of cephalexin and cefuroxime axetil in healthy volunteers.
Ding Yi, Liu WenXing, Jia YanYan et al. · J Clin Pharmacol · 2013
PMID: 23400747RCT
Cefuroxime as a prophylactic preoperative antibiotic in septoplasty. A double blind randomized placebo controlled study.
Lilja Marcus, Mäkitie Antti A, Anttila Veli-Jukka et al. · Rhinology · 2011
PMID: 21468376RCT
Antibiotic prophylaxis in primary hip and knee arthroplasty: comparison between cefuroxime and two specific antistaphylococcal agents.
Tyllianakis Minos E, Karageorgos Athanasios Ch, Marangos Markos N et al. · J Arthroplasty · 2010
PMID: 20381287RCT

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type
Substance / Medication
Fully Specified Name
Cefuroxime (substance)
SNOMED CT
372833007
UMLS CUI
C0007562
RxNorm CUI
2194

Clinical Data

This intervention maps to 17 entities in the Ltrl knowledge graph.

17
Conditions
0
Biomarkers
0
Specialists
0
Symptoms
133
Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Ltrl clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.